Effects of 30 days of creatine ingestion in older men
Rawson ES, Wehnert ML, Clarkson PM
European journal of applied physiology and occupational physiology · 79 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 1999-06-01 · Eur J Appl Physiol Occup Physiol · vol. 80 · número 2 · págs. 139–144
- Editorial
- Springer Science+Business Media
- Citado
- 128 citas · más que el 87% de estudios similares · 2.3× el promedio de su campo
- Referencias
- 0 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Nutrition and Health in Aging · Biochemical effects in animals
- Palabras clave
- creatine supplementation, older men, muscle fatigue, knee extensors, elbow flexors, muscle strength, body composition, fat-free mass
- MeSH
- leg, muscle, skeletal, humans, creatine, exercise, double-blind method, body composition, muscle fatigue, isometric contraction, aged, aged, 80 and over, middle aged, male
3 autores
- Eric S. Rawson🇺🇸University of Massachusetts Amherst
- Melissa L. Wehnert🇺🇸University of Massachusetts Amherst
- Priscilla M. Clarkson🇺🇸University of Massachusetts Amherst
Resumen
El texto original del estudio, en el idioma en que se publicó.
In this investigation we evaluated the effects of oral creatine (Cr) supplementation on body composition, strength of the elbow flexors, and fatigue of the knee extensors in 20 males aged 60-82 years who were randomly administered Cr or placebo (P) in a double-blind fashion. Subjects ingested either 20 g of Cr or P for 10 days, followed by either 4 g of Cr or P, respectively, for 20 days. Tests were conducted pre-supplementation and following 10 and 30 days of supplementation. Leg fatigue was determined using an isokinetic dynamometer; subjects performed 5 sets of 30 maximal voluntary contractions at 180 degrees x s(-1), with 1 min of recovery between sets. The strength of the elbow flexors was assessed using a modified preacher bench attached to a strain gauge. There was a significant interaction (P < 0.05; group x time) in leg fatigue following supplementation. However, this interaction appears to have resulted from a combination of the improved fatigue score by the Cr-supplemented group and the decreased fatigue score by the P-supplemented group, because when the simple main effects were analyzed for the groups individually, there was no significant difference over time for either of the groups. There were no significant differences in body mass, body density, or fat-free mass as assessed by hydrostatic weighing, or strength between the Cr-supplemented or P-supplemented groups. These data suggest that 30 days of Cr-supplementation may have a beneficial effect on reducing muscle fatigue in men over the age of 60 years, but it does not affect body composition or strength.
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