Creatine enhances oxygen uptake and performance during alternating intensity exercise
Rico-Sanz J, Mendez Marco MT
Medicine and science in sports and exercise · 28 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2000-02-01 · Med Sci Sports Exerc · vol. 32 · número 2 · pág. 379
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 65 citas · más que el 85% de estudios similares · 2.1× el promedio de su campo
- Referencias
- 25 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Cardiovascular and exercise physiology · Sports Performance and Training
- Palabras clave
- creatine supplementation, creatine monohydrate, oxygen consumption, time to exhaustion, blood ammonia, plasma uric acid, creatine kinase, well-trained cyclists, exercise performance
- MeSH
- humans, creatine, exercise, oxygen consumption, muscle fatigue, exercise tolerance, muscle contraction, dietary supplements, adult, male
2 autores
- J. Rico‐Sanz🇪🇸Universitat Autònoma de Barcelona
- María Teresa Méndez Marco🇪🇸Universidad Complutense de Madrid; Universitat Autònoma de Barcelona
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
The main purpose of the present study was to measure the total oxygen consumed, accumulation of blood metabolites, and performance during alternating intensity exercise before and after a period of creatine (Cr) loading in well-trained humans.
Methods
Fourteen males were randomly assigned to two groups of seven males and were tested before and after 5 d of placebo (PL) or Cr monohydrate (CR) loading (20 g x d(-1)). Oxygen uptake was measured using a breath-by-breath system during bicycle exercise alternating every 3 min between bouts at 30%(-30%) and 90% (-90%) of the maximal power output to exhaustion. Blood samples were also obtained at rest, before the end of each cycling load, at exhaustion, and 5-min postexercise.
Results
The oxygen consumed during 1-90% (5.08 +/- 0.39 L) and 2-90% (5.32 +/- 0.30 L) was larger after CR (5.67 +/- 0.34 and 5.78 +/- 0.35 L, P < 0.01 and P < 0.05, respectively). Blood ammonia accumulation at the end of 1-90% (23.1 +/- 6.5 micromol x L(-1)) and 3-30% (64.7 +/- 15.2 micromol x L(-1)) was lower after CR (P < 0.05), whereas plasma uric acid accumulation was lower at exhaustion (P < 0.05) and 5-min postexercise (P < 0.01). Time to exhaustion increased (P < 0.05) from 29.9 +/- 3.8 to 36.5 +/- 5.7 min after CR, whereas it remained the same after PL.
Conclusions
The results indicate that Cr feeding increases the capacity of human muscle to perform work during alternating intensity contraction, possibly as a consequence of increased aerobic phosphorylation and flux through the creatine kinase system.
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