Effect of creatine loading on long-term sprint exercise performance and metabolism
Preen D, Dawson B, Goodman C, Lawrence S, Beilby J, Ching S
Medicine and science in sports and exercise · 31 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2001-05-01 · Med Sci Sports Exerc · vol. 33 · número 5 · págs. 814–821
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 73 citas · más que el 77% de estudios similares · 1.3× el promedio de su campo
- Referencias
- 0 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Sports Performance and Training · Biochemical effects in animals
- Palabras clave
- creatine supplementation, creatine loading, repeated sprint exercise, peak power, phosphocreatine, muscle creatine, muscle metabolism, vastus lateralis, creatine kinase, phosphoenolpyruvate, phosphatidylcholine
- MeSH
- muscle, skeletal, humans, creatine, placebos, administration, oral, task performance and analysis, oxygen consumption, physical endurance, running, dietary supplements, adult, male
6 autores
- David Brian Preen🇦🇺The University of Western Australia
- BRIAN T. DAWSON🇦🇺The University of Western Australia; Queen Elizabeth II Medical Centre
- Carmél Goodman🇦🇺The University of Western Australia; Queen Elizabeth II Medical Centre
- Steven R. Lawrence🇦🇺The University of Western Australia; Queen Elizabeth II Medical Centre
- John P. Beilby🇦🇺The University of Western Australia; Queen Elizabeth II Medical Centre
- Simon Ching🇦🇺The University of Western Australia; Queen Elizabeth II Medical Centre
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
This study examined whether creatine (Cr) supplementation could enhance long-term repeated-sprint exercise performance of approximately 80 min in duration.
Methods
Fourteen active, but not well-trained, male subjects initially performed 10 sets of either 5 or 6 x 6 s maximal bike sprints, with varying recoveries (24, 54, or 84 s between sprints) over a period of 80 min. Work done (kJ) and peak power (W) were recorded for each sprint, and venous blood was collected preexercise and on four occasions during the exercise challenge. Muscle biopsies (vastus lateralis) were obtained preexercise as well as 0 min and 3 min postexercise. Subjects were then administered either 20 g.d-1 Cr.H2O (N = 7) or placebo (N = 7) for 5 d. Urine samples were collected for each 24 h of the supplementation period. Subjects were then retested using the same procedures as in test 1.
Results
Total work done increased significantly (P < 0.05) from 251.7 +/- 18.4 kJ presupplementation to 266.9 +/- 19.3 kJ (6% increase) after Cr ingestion. No change was observed for the placebo group (254.0 +/- 10.4 kJ to 252.3 +/- 9.3 kJ). Work done also improved significantly (P < 0.05) during 6 x 6 s sets with 54-s and 84-s recoveries and approached significance (P = 0.052) in 5 x 6 s sets with 24-s recovery in the Cr condition. Peak power was significantly increased (P < 0.05) in all types of exercise sets after Cr loading. No differences were observed for any performance variables in the placebo group. Resting muscle Cr and PCr concentrations were significantly elevated (P < 0.05) after 5 d of Cr supplementation (Cr: 48.9%; PCr: 12.5%). Phosphocreatine levels were also significantly higher (P < 0.05) immediately and 3 min after the completion of exercise in the Cr condition.
Conclusion
The results of this study indicate that Cr ingestion (20 g.day-1 x 5 d) improved exercise performance during 80 min of repeated-sprint exercise, possibly due to an increased TCr store and improved PCr replenishment rate.
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