Dietary creatine supplementation and muscular adaptation to resistive overload
Stevenson SW, Dudley GA
Medicine and science in sports and exercise · 25 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2001-08-01 · Med Sci Sports Exerc · vol. 33 · número 8 · págs. 1304–1310
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 47 citas · más que el 74% de estudios similares · 1.1× el promedio de su campo
- Referencias
- 30 trabajos
- Acceso
- De pago · PUBLIC-DOMAIN
- Áreas de investigación
- Muscle metabolism and nutrition · Sports Performance and Training · Biochemical effects in animals
- Palabras clave
- electromyostimulation, resistance training, muscle hypertrophy, quadriceps, muscle fatigue, muscle torque, cross-sectional area, ergogenic aids
- MeSH
- muscle, skeletal, humans, hypertrophy, creatine, electric stimulation therapy, muscle fatigue, weight lifting, dietary supplements, adult, female, male, biomechanical phenomena, ergonomics
2 autores
- Scott Walter Stevenson🇺🇸California State Polytechnic University
- Gary A. Dudley🇺🇸University of Georgia; California State Polytechnic University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
This study examined the influence of dietary creatine (CR) supplementation upon mechanical and hypertrophic responses to a well-defined conditioning stimulus provided by electromyostimulation (EMS).
Methods
Eighteen resistance-trained subjects were assigned CR or a placebo (PL) in a randomized, double-blind fashion. After CR loading (20 g x d(-1) for 7 d), CR supplementation (5 g x d(-1)) or PL was continued for 8 wk. During supplementation, EMS (3--5 sets of 10 coupled eccentric and concentric actions) was applied to the left m. quadriceps femoris (QF) twice weekly while subjects continued voluntary resistance training of both lower limbs unsupervised. Cross-sectional area (CSA) of each QF was assessed with magnetic resonance imaging (MRI). Torque during EMS was analyzed to assess muscle loading and fatigue resistance.
Results
Maximal torque and the torque time integral increased markedly over training (P < or = 0.0001). These responses reflected activation of more muscle as EMS current was increased (about 16%), greater recovery between sets (P < or = 0.0423), and less fatigue during sets over training (P = 0.0002). CR did not influence these responses (P = 0.8093). In accord with these results, the increase in CSA for the stimulated QF (11%) was comparable for CR and PL (P = 0.2190). CSA in the nonstimulated QF increased 5% in CR (P = 0.0091) but did not change in PL.
Conclusion
We conclude that CR supplementation did not augment the mechanical or hypertrophic response to a precisely measured conditioning stimulus that attenuated but did not ameliorate fatigue. We suggest that enhanced fatigue resistance may not explain the apparent ergogenic effect of CR during voluntary training.
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