Effect of caffeine and ephedrine ingestion on anaerobic exercise performance
Bell DG, Jacobs I, Ellerington K
Medicine and science in sports and exercise · 90 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2001-08-01 · Med Sci Sports Exerc · vol. 33 · número 8 · págs. 1399–1403
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 189 citas · más que el 95% de estudios similares · 4.8× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 19 trabajos
- Acceso
- De pago
- Áreas de investigación
- Coffee research and impacts · Sports Performance and Training · Cardiovascular and exercise physiology
- Palabras clave
- caffeine, ephedrine, anaerobic exercise performance, time to exhaustion, Wingate test, accumulated oxygen deficit, blood lactate, blood glucose, catecholamines, central nervous system stimulation, ergogenic aids
- MeSH
- humans, ephedrine, catecholamines, dopamine, caffeine, central nervous system stimulants, exercise, energy metabolism, physical endurance, adult, male
3 autores
- Doug G Bell
- Ira Allen Jacobs
- KRISTINA ELLERINGTON
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
Ingestion of a combination of caffeine (C) and ephedrine (E) prolongs time to exhaustion during high-intensity aerobic exercise. CNS stimulation by C and E was proposed as part of the mechanism for the improvement. It was thought that this arousal might also be of benefit during anaerobic exercise. The purpose of this study was to investigate the effect of C, E, and C+E ingestion on performance of anaerobic exercise.
Methods
Two groups were used to evaluate the effect of C and E on anaerobic performance. Group 1 (WIN) consisted of 16 healthy untrained male subjects who performed a 30-s Wingate test. Group 2 (MAOD) consisted of 8 healthy untrained male subjects who performed a supramaximal (125%VO(2peak)) cycle exercise trial to exhaustion to determine maximum accumulated oxygen deficit. The trials commenced 1.5 h after ingesting either C (5 mg x kg(-1)), E (1 mg x kg(-1)), a combination of C+E, or a placebo (P). All trials were randomized and double blind. Blood samples were assayed for lactate and glucose post drug ingestion just before exercise, and again 3, 5, and 10 min post exercise. Catecholamines were measured in the preexercise and 10-min postexercise blood samples.
Results
Ephedrine increased power output during the early phase of the Wingate test, whereas C increased time to exhaustion and O(2) deficit during the MAOD test. C, E, and C+E increased blood lactate, glucose, and catecholamine levels.
Conclusion
The improvement in anaerobic exercise performance is likely a result of both stimulation of the CNS by E and skeletal muscle by C.
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