Financiado en parte por Grains Research and Development Corporation
Effects of monounsaturated enriched sunflower oil on CHD risk factors including LDL size and copper-induced LDL oxidation
Ashton EL, Best JD, Ball MJ
Journal of the American College of Nutrition · 15 citas
Etiquetas de revisión
Financiado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiado por la industria
- Grupo de la industria
- Grains Research and Development Corporation
Según 1 financiador declarado.
Publicación
- Publicado
- 2001-08-01 · J Am Coll Nutr · vol. 20 · número 4 · págs. 320–326
- Editorial
- Taylor & Francis
- Citado
- 42 citas · más que el 80% de estudios similares · 1.2× el promedio de su campo
- Referencias
- 37 trabajos
- Acceso
- Acceso abierto (copia en repositorio) · CC-BY
- Áreas de investigación
- Fatty Acid Research and Health · Lipoproteins and Cardiovascular Health · Nuts composition and effects
- Palabras clave
- monounsaturated fatty acids, sunflower oil, coronary risk factors, LDL oxidation, LDL particle size, HDL cholesterol, HDL3 cholesterol, insulin, low-fat high-carbohydrate diet, dietary fat composition, isocaloric substitution, postmenopausal women, middle-aged men
- MeSH
- humans, coronary disease, copper, cholesterol, insulin, dietary carbohydrates, blood glucose, triglycerides, lipoproteins, ldl, plant oils, diet, fat-restricted, risk factors, cross-over studies, lipid peroxidation, energy intake, postmenopause, adult, middle aged, female, male, cholesterol, ldl, cholesterol, hdl, sunflower oil
3 autores
- Emma Ashton🇦🇺University of Tasmania
- James Donovan Best🇦🇺St Vincent's Hospital Melbourne
- Madeleine J. Ball🇦🇺 · autor de correspondenciaUniversity of Tasmania
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
To compare the effects of a diet high in monounsaturated enriched sunflower oil and a low fat diet on CHD risk factors including in vitro Cu-induced LDL oxidation and LDL size, lipids, lipoproteins, glucose and insulin.
Design
A randomized crossover dietary intervention.
Setting
Free living individuals.
Subjects
Fourteen healthy males 35 to 55 years of age and 14 healthy postmenopausal women 50 to 60 years of age completed the dietary intervention. Two subjects did not complete the study, and their data were not included.
Interventions
A low fat, high carbohydrate diet (22% to 25% of energy from total fat, 7% to 8% of energy from monounsaturated fat and 55% to 60% of energy from carbohydrate) was compared to a monounsatutated enriched sunflower oil (MO) diet (40% to 42% of energy from fat, with 26% to 28% from monounsaturated fat and 40% to 45% of energy from carbohydrate) in an isocaloric substitution. Each dietary period was one month.
Results
Total cholesterol, LDL cholesterol, triglycerides and glucose were not significantly different between the two diets. HDL cholesterol, HDL3 cholesterol and insulin were significantly higher on the MO diet, mean 7%, 7% and 17% higher respectively. Copper-induced LDL oxidation lag phase was significantly longer (mean 18%) after the MO diet compared to the low fat, high carbohydrate diet. LDL particle size was not significantly different.
Conclusions
The significant increase in LDL oxidation lag phase and the significantly higher HDL cholesterol on the MO diet would be expected to be associated with a decrease in CHD risk.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.