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Ensayo controlado aleatorizado2001

Caffeine as a lipolytic food component increases endurance performance in rats and athletes

Ryu S, Choi SK, Joung SS, Suh H, Cha YS, Lee S, Lim K

Journal of nutritional science and vitaminology · 40 citas

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas, más trabajo en animales o laboratorio
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Universidad u hospital
Kyungpook National University

Según 1 financiador declarado.

Publicación

Publicado
2001-01-01 · J Nutr Sci Vitaminol (Tokyo) · vol. 47 · número 2 · págs. 139–146
Editorial
Center for Academic Publications Japan
Citado
84 citas · más que el 79% de estudios similares · 1.2× el promedio de su campo
Referencias
37 trabajos
Acceso
Acceso abierto (publicación gratuita)
Áreas de investigación
Coffee research and impacts · Muscle metabolism and nutrition · Sports Performance and Training
Palabras clave
caffeine, ergogenic aids, endurance performance, lipolysis, fat oxidation, glycogen sparing, free fatty acids, glycerol, respiratory exchange ratio, blood lactate, time to exhaustion, physical activity
MeSH
adipose tissue, animals, humans, rats, rats, sprague-dawley, lactates, caffeine, glycogen, fatty acids, nonesterified, breath tests, exercise test, physical conditioning, animal, lipolysis, oxygen consumption, respiration, physical endurance, bicycling, adult, male, physical exertion

7 autores

  • Ryu Sungpil
  • Sung-Keun Choi🇰🇷Kyung-in Women's University
  • Seung-Sam Joung🇰🇷Kyung-in Women's University
  • Heajung Suh🇰🇷Kyungpook National University
  • Youn‐Soo Cha🇰🇷Jeonbuk National University
  • Soochun LEE🇰🇷Kyungpook National University
  • Kiwon Lim

Resumen

El texto original del estudio, en el idioma en que se publicó.

Caffeine is one of the famous ergogenic aids in the athletic field. Caffeine has been known to stimulate lipolysis that spares stored glycogen utilization during moderate intensity exercise. Therefore, we investigated the effects of caffeine ingestion on exercise performance in rats and athletes. Rats were administered the caffeine (6 mg/kg) 1 h prior to the exercise then were run on a treadmill at a speed of 20 m/min. They were decapitated at 0 min, 30 min, 60 min of exercise, and exhausted time point. Human subjects ingested the caffeine (5 mg/kg) 1 h prior to the exercise. They exercised on a cycle ergometer at 60% of their VO2max for 45 min, and then the exercise intensity was increased to 80% of their VO2max until exhaustion. Blood and breathing gas samples were collected and calculated every 10 min during exercise. Respiratory exchange ratio of the caffeine trial was significantly lower than that of the placebo trial in the athletes' study (p<0.05). Blood free fatty acid (FFA) levels in studies of both rats and athletes were increased by caffeine ingestion during exercise (p<0.05). Blood lactate levels were also increased during exercise in both rats and athletes (p<0.05). Increased FFA and glycerol concentrations reduced glycogen utilization during exercise compared with placebo group in rats. In addition, endurance time to exhaustion was significantly increased by the caffeine ingestion in both rats and athletes (p<0.05). These results suggest that the caffeine ingestion enhanced endurance performance resulting from spare stored glycogen with increasing lipolysis from adipose tissues and fat oxidation during exercise both in rats and in athletes.

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