Effects of palm oil and dietary cholesterol on plasma lipoproteins: results from a dietary crossover trial in free-living subjects
Bautista LE, Herrán OF, Serrano C
European journal of clinical nutrition · 8 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2001-08-30 · Eur J Clin Nutr · vol. 55 · número 9 · págs. 748–754
- Editorial
- Springer Nature
- Citado
- 12 citas · más que el 22% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 41 trabajos
- Acceso
- De pago
- Áreas de investigación
- Fatty Acid Research and Health · Cholesterol and Lipid Metabolism · Lipoproteins and Cardiovascular Health
- Palabras clave
- palm oil, dietary cholesterol, egg consumption, serum lipoproteins, LDL cholesterol, HDL cholesterol, total cholesterol, triglycerides, palmitic acid, saturated fat, dietary fat intake, healthy young men
- MeSH
- humans, cardiovascular diseases, cholesterol, dietary, triglycerides, plant oils, cross-over studies, double-blind method, time factors, eggs, adult, male, cholesterol, ldl, cholesterol, hdl, palm oil
3 autores
- Le Bautista🇨🇴 · autor de correspondenciaUniversidad Industrial de Santander
- OF Herrán🇨🇴Universidad Industrial de Santander
- C Serrano
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
To study the effects of palm oil (PO) and egg consumption (E) on plasma lipoproteins.
Design
Randomized crossover trial.
Setting
Free-living subjects.
Subjects
Twenty-eight healthy male students aged 20-34 y.
Interventions
Four typical Colombian diets (10 878 kJ/day; 57% energy in carbohydrates, 12% energy in proteins and 31% energy in fats) were consumed for 4 weeks. The HPOLC diet was high in PO (8.8% energy as palmitic acid, PA) and low in eggs (181.2 mg/kJ of dietary cholesterol, DC); the HPOHC diet was high in PO and high in eggs (866.1 mg/kJ of DC); the MPOMC diet was moderate in PO (6.3% energy as PA) and moderate in eggs (581.6 mg/kJ of DC); and the LOPOMC diet had no PO and was moderate in eggs (543.9 mg/kJ of DC).
Main outcome
Total (TC), low density (LDL-c), and high density lipoprotein cholesterol (HDL-c), and triacylglycerols (TAG) were measured on a pool of three fasting blood samples collected in consecutive days the last week of each diet.
Results
Comparison of the HPOHC and HPOLC diets showed increases in TC and LDL-c of 0.21 (P=0.01), and 0.16 mmol/l (P=0.05). Comparison of LOPOMC and MPOMC diets showed increases in TC and LDL-c of 0.39 (P<0.001), and 0.38 mmol/l (P<0.001), respectively. No significant changes in HDL-c or TAG were observed.
Conclusions
Our findings suggest that non-extreme short-term changes in PO and DC consumption lead to significant elevations in plasma TC and LDL-c.
Sponsorship
CENIPALMA, Fundación Cardiovascular del Oriente Colombiano, Universidad Industrial de Santander.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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