Opposite actions of caffeine and creatine on muscle relaxation time in humans
Hespel P, Op't Eijnde B, Van Leemputte M
Journal of applied physiology (Bethesda, Md. : 1985) · 44 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2002-02-01 · J Appl Physiol (1985) · vol. 92 · número 2 · págs. 513–518
- Editorial
- American Physiological Society
- Citado
- 78 citas · más que el 74% de estudios similares · 1.0× el promedio de su campo
- Referencias
- 32 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Coffee research and impacts · Sports Performance and Training
- Palabras clave
- caffeine, creatine supplementation, muscle relaxation time, muscle torque, quadriceps, muscle fatigue, contraction time
- MeSH
- knee, muscle, skeletal, humans, creatine, caffeine, cross-over studies, double-blind method, electric stimulation, reaction time, muscle contraction, muscle relaxation, torque, time factors, adult, female, male
3 autores
- Peter Hespel🇧🇪KU Leuven
- Bert O. Eijnde🇧🇪KU Leuven
- Marc Van Leemputte🇧🇪KU Leuven
Resumen
El texto original del estudio, en el idioma en que se publicó.
The effect of creatine and caffeine supplementation on muscle torque generation and relaxation was investigated in healthy male volunteers. Maximal torque (T(max)), contraction time (CT) from 0.25 to 0.75 of T(max), and relaxation time (RT) from 0.75 to 0.25 of T(max) were measured during an exercise test consisting of 30 intermittent contractions of musculus quadriceps (2 s stimulation, 2 s rest) that were induced by electrical stimulation. According to a double-blind randomized crossover design, subjects (n = 10) performed the exercise test before (pretest) and after (posttest) creatine supplementation (Cr, 4 x 5 g/day, 4 days), short-term caffeine intake (Caf, 5 mg x kg(-1) x day(-1), 3 days), creatine supplementation + short-term caffeine intake (Cr+Caf), acute caffeine intake (ACaf, 5 mg/kg) or placebo. Compared with placebo, Cr shortened RT by approximately 5% (P < 0.05). Conversely, Caf increased RT (+ approximately 10%, P < 0.05), in particular as RT increased because of fatigue. RT was not significantly changed by either Cr+Caf or ACaf. T(max) and CT were similar during all experimental conditions. Initial T(max) was approximately 20% of voluntary maximal isometric contraction force, which was not different between treatments. It is concluded that Caf intake (3 days) prolongs muscle RT and by this action overrides the shortening of RT due to creatine supplementation.
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