Impact of diets containing corn oil or olive/sunflower oil mixture on the human plasma and lipoprotein lipid metabolism
Wagner KH, Tomasch R, Elmadfa I
European journal of nutrition · 30 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Biomarcadores de consumo
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2001-08-01 · Eur J Nutr · vol. 40 · número 4 · págs. 161–167
- Editorial
- Springer Science+Business Media
- Citado
- 62 citas · más que el 79% de estudios similares · 1.2× el promedio de su campo
- Referencias
- 28 trabajos
- Acceso
- De pago
- Áreas de investigación
- Fatty Acid Research and Health · Edible Oils Quality and Analysis · Lipid metabolism and biosynthesis
- Palabras clave
- corn oil, olive oil, sunflower oil, oil blends, monounsaturated fatty acids, polyunsaturated fatty acids, oleic acid, linoleic acid, LDL cholesterol, HDL cholesterol, VLDL triglycerides, total cholesterol, triglycerides, tocopherols, alpha-tocopherol, gamma-tocopherol, lipoprotein metabolism
- MeSH
- humans, vitamin e, cholesterol, corn oil, triglycerides, lipoproteins, hdl, plant oils, alpha-tocopherol, gamma-tocopherol, antioxidants, cross-over studies, double-blind method, adult, male, cholesterol, ldl, cholesterol, hdl, cholesterol, vldl, olive oil, sunflower oil
3 autores
- Karl‐Heinz Wagner🇦🇹University of Vienna
- R. Tomasch🇦🇹University of Vienna
- Ibrahim Elmadfa🇦🇹University of Vienna
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The effects of monounsaturated fatty acids (MUFA) rich diets compared to those that are rich in polyunsaturated fatty acids (PUFA) as well as the effects of an intake of single oils compared to oil mixtures are controversially discussed and results are contradictory.
Aim of this study
To evaluate the effects of a plant oil-mixture (olive/sunflower oil; saturated/monounsaturated/polyunsaturated (S/M/P) = 14:69:17) high in oleic acid but also showing a moderate content of polyunsaturated fatty acids (PUFA) in comparison with a single, PUFA rich corn oil (S/M/P = 13:33:54) used in a normal, balanced diet on human plasma and lipoprotein metabolism.
Methods
The double-blind designed study comprised 28 healthy, non-smoking young men aged between 19 and 31 years. After two weeks of adjustment (mixed, balanced diet: 11.6 MJ average, average fat intake approximately 105 g/d), the design included a two week test period in which a diet with 80 g corn oil/d vs a mixture of 68 g olive- and 12 g sunflower oil/d (total 80 g) as the main fat source was given, followed by a crossover after two weeks. Compliance and ingestion of diets were monitored by assessing the fatty acid pattern in LDL and by determination of alpha- and gamma-tocopherol in plasma and LDL. Results Diets were well incorporated due to the significant changes in plasma- and LDL-tocopherol levels and the significant different average ratio of oleic acid to linoleic acid in LDL. The PUFA-rich corn oil diet was able to reduce low density lipoprotein (LDL) cholesterol from adjustment to T2 significantly (p < 0.01), which was also confirmed by a trend after cross over (p=0.15). Total cholesterol (only after cross over at T3), total triglycerides (TG) and very low density lipoprotein (VLDL)-TG were significantly lower at T2 after the corn oil diet than after the mixed oil diet. Total high density lipoproteins (HDL) and HDL cholesterol remained unchanged by both diets.
Conclusions
The results show that during the intervention of two weeks for each diet and the following cross over the corn oil diet had more influence on lipoprotein metabolism than the MUFA-rich diet. The hypocholesteremic effect of the PUFA-rich diet must also be connected with the high amount of unsaponifiable substances, mainly phytosterols in the corn oil.
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