The effects of fish oil and isoflavones on delayed onset muscle soreness
Lenn J, Uhl T, Mattacola C, Boissonneault G, Yates J, Ibrahim W, Bruckner G
Medicine and science in sports and exercise · 85 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2002-10-01 · Med Sci Sports Exerc · vol. 34 · número 10 · págs. 1605–1613
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 140 citas · más que el 93% de estudios similares · 4.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 69 trabajos
- Acceso
- De pago
- Áreas de investigación
- Exercise and Physiological Responses · Muscle metabolism and nutrition · Fatty Acid Research and Health
- Palabras clave
- fish oil, isoflavones, soy protein isolate, delayed onset muscle soreness, omega-3 fatty acids, exercise-induced muscle damage, inflammation, eicosanoid pathway, interleukin-6, TNF-α, malondialdehyde, creatine kinase, dietary supplementation
- MeSH
- humans, myositis, pain, isoflavones, creatine kinase, fatty acids, fish oils, pain measurement, exercise, adult, female, male
7 autores
- Jon D. Lenn🇺🇸University of Kentucky
- Tim L. Uhl🇺🇸University of Kentucky
- Carl G. Mattacola🇺🇸University of Kentucky
- Gilbert A. Boissonneault🇺🇸University of Kentucky
- J. W. Yates🇺🇸University of Kentucky
- Wissam H. Ibrahim🇺🇸University of Kentucky
- Geza G. Bruckner🇺🇸University of Kentucky
Resumen
El texto original del estudio, en el idioma en que se publicó.
Introduction/purpose
Fish oils (FO) have been shown to modulate the inflammatory response through alteration of the eicosanoid pathway. Isoflavones (ISO) appear to reduce the inflammatory pathway through their role as a tyrosine kinase inhibitor. Delayed onset muscle soreness (DOMS) develops after intense exercise and has been associated with an inflammatory response. Therefore, we hypothesized that physical parameters associated with DOMS could be decreased via the modulation of the inflammatory response by supplementing subjects with either FO or ISO.
Methods
22 subjects were recruited and randomly assigned to one of three treatment groups: FO (1.8 g of omega-3 fatty acids x d(-1)), ISO (120 mg soy isolate x d(-1)), or placebo (PL) (Western fat blend and/or wheat flour). All treatment groups received 100-IU vitamin E x d(-1) to minimize lipid peroxidation of more highly unsaturated fatty acids. Subjects were supplemented 30 d before the exercise and during the week of testing and were instructed to refrain from unusual exercise. DOMS was induced by 50 maximal isokinetic eccentric elbow flexion contractions. Strength parameters, pain, arm circumference, and relaxed arm angle (RANG) were measured at 48, 72, and 168 h post exercise. Cortisol, creatine kinase (CK), interleukin-6 (IL-6), tumor necrosis factor (TNFalpha), malondialdehyde (MDA), and serum iron were measured before supplementation, after supplementation, and post exercise.
Results
Significant decreases were observed in RANG and strength 48 h postexercise among all groups, and there were significant increases in pain and arm circumference. There were no significant changes among all groups from baseline at 168 h (7 d) post exercise. There were no significant treatment effects between groups for the physical parameters or for cortisol, CK, IL-6, TNFalpha, MDA, or serum iron.
Conclusion
These data indicate FO or ISO, at the doses supplemented, were not effective in ameliorating DOMS with the above-cited protocol.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.