Interactions between alcohol and caffeine in relation to psychomotor speed and accuracy
Mackay M, Tiplady B, Scholey AB
Human psychopharmacology · 39 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2002-01-29 · Hum Psychopharmacol · vol. 17 · número 3 · págs. 151–156
- Editorial
- Wiley
- Citado
- 55 citas · más que el 70% de estudios similares · 0.6× el promedio de su campo
- Referencias
- 27 trabajos
- Acceso
- De pago
- Áreas de investigación
- Coffee research and impacts · Substance Abuse Treatment and Outcomes · Alcohol Consumption and Health Effects
- Palabras clave
- alcohol, caffeine, psychomotor speed, response accuracy, reaction time, Digit Symbol Substitution Test, error rate, central nervous system depressants
- MeSH
- humans, ethanol, caffeine, analysis of variance, chi-square distribution, alcohol drinking, psychomotor performance, reaction time, drug interactions, adult, female, male
3 autores
- Michelle Mackay🇬🇧Northumbria University
- Brian Tiplady🇬🇧AstraZeneca (United Kingdom)
- Andrew B Scholey🇬🇧 · autor de correspondenciaNorthumbria University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Unlike other CNS depressants, alcohol intoxication can be associated with increased error rates, coupled with unaffected (or speeded) response rates during psychomotor and cognitive processing. The present study examined whether concurrent consumption of caffeine may differentially affect these aspects of alcohol and performance.A randomised, double-blind, placebo-controlled design was utilised in which 64 healthy young volunteers received either 0.66 g/kg alcohol, caffeine (110-120 mg), both or neither. Performance was assessed using a four choice reaction time task (FCRT) with elements of repetitive (predictable) and random stimuli sequences and the digit symbol substitution task (DSST). Individuals on alcohol made significantly more errors during both fixed and random FCRT sequences, and there was evidence of weak antagonism of these effects by caffeine on the latter measure. On the DSST test of psychomotor speed, alcohol was associated with a significant slowing, the caffeine group were significantly faster and there was clear antagonism of the effects of alcohol by caffeine. These findings confirm that alcohol consumption is associated a greater number of errors and provide some evidence for task-specific antagonism of alcohol's cognitive effects by caffeine.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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