A study to assess the effects of a new detergent-free, olive oil formulation dentifrice in vitro and in vivo
Pretty IA, Gallagher MJ, Martin MV, Edgar WM, Higham SM
Journal of dentistry · 13 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas, más trabajo en animales o laboratorio
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Institute for Health and Care Research
- Gobierno
- National Institute for Health Research (NIHR)
- Subvenciones
- National Institute for Health and Care Research (DHCS/05/05/008)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2003-06-02 · J Dent · vol. 31 · número 5 · págs. 327–332
- Editorial
- Elsevier BV
- Citado
- 28 citas · más que el 71% de estudios similares · 0.4× el promedio de su campo
- Referencias
- 33 trabajos
- Acceso
- De pago
- Áreas de investigación
- Oral microbiology and periodontitis research · Dental Health and Care Utilization · Essential Oils and Antimicrobial Activity
- Palabras clave
- olive oil, toothpaste, plaque inhibition, bacterial growth inhibition, fluoride toothpaste, plaque index, oral hygiene
- MeSH
- dental plaque, humans, bacteria, fluorides, plant oils, cariostatic agents, dentifrices, colony count, microbial, dental plaque index, cross-over studies, double-blind method, materials testing, bacterial adhesion, chemistry, pharmaceutical, adult, olive oil
5 autores
- Iain Pretty🇬🇧University of Liverpool
- Malcolm Gallagher🇬🇧University of Liverpool
- M.V. Martín🇬🇧University of Liverpool
- W.M. Edgar🇬🇧University of Liverpool
- S.M. Higham🇬🇧University of Liverpool
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
To determine the effects of a detergent-free dentifrice containing olive oil using in vitro microbiological tests and an in vivo plaque re-growth model.
Method
A total of 20 subjects took part in a double blind, single-centre, crossover study in which slurry rinses were the only form of plaque control over a 5-day period. Following a washout and prophylaxis the subjects used 2x daily rinses in the absence of all other plaque control methods. Subjects returned to the clinic on the afternoon of day 5 when plaque was disclosed and assessed by plaque index and area. A further 9-day washout was carried out and the rinse period repeated to ensure that each subject had used both experimental and control slurries. In vitro microbiological experiments were conducted to examine the effects of olive oil alone and in the new dentifrice on bacterial growth and adhesion.
Results
20 subjects completed the trial. The olive oil product showed a significant inhibition of plaque re-growth (17.2%) compared with a fluoride-matched control using the Turesky index (p<0.0001) and also using the planimetric technique (22.0%) (p<0.0001). Significant decreases in bacterial growth and adhesion (measured as total viable count) were detected in the presence of olive oil and the new dentifrice.
Conclusion
The results suggest that the experimental olive oil containing paste has potential value in the inhibition of plaque.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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