Effects of vitamin D supplementation on strength, physical performance, and falls in older persons: a systematic review
Latham NK, Anderson CS, Reid IR
Journal of the American Geriatrics Society · 117 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2003-08-15 · J Am Geriatr Soc · vol. 51 · número 9 · págs. 1219–1226
- Editorial
- Wiley
- Citado
- 192 citas · más que el 60% de estudios similares · 0.9× el promedio de su campo
- Referencias
- 37 trabajos
- Acceso
- De pago
- Áreas de investigación
- Vitamin D Research Studies · Balance, Gait, and Falls Prevention · Nutrition and Health in Aging
- Palabras clave
- vitamin D supplementation, older adults, falls, physical performance, muscle strength, vitamin D metabolites, calcium supplementation, fall prevention
- MeSH
- muscle, skeletal, humans, calcium, hydroxycholecalciferols, vitamin d, placebos, drug therapy, combination, exercise, administration, oral, confidence intervals, risk, accidental falls, age factors, sex factors, health status, time factors, physical fitness, dietary supplements, aged, aged, 80 and over, middle aged, female, male, randomized controlled trials as topic
3 autores
- Nancy K. Latham🇺🇸🇳🇿 · autor de correspondenciaBoston University; University of Auckland
- Craig S. Anderson🇳🇿University of Auckland
- Ian R. Reid🇳🇿University of Auckland
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
identify, appraise, and synthesize data from randomized, controlled trials of vitamin D supplementation in older people.
Design
A systematic review of trials identified from searches of databases, reference lists, review articles, and recent conference proceedings.
Setting
Most studies performed in ambulatory setting.
Participants
Older people (mean age=60).
Interventions
Vitamin D or vitamin D metabolites.
Measurements
Strength, physical performance, or falls.
Results
Thirteen trials involving 2,496 patients met this study's inclusion criteria. Most of the trials were small and had methodological problems. In 10 trials, there was no evidence that vitamin D or vitamin D metabolites had an effect on falls or physical function, but three trials showed a positive effect of vitamin D in combination with calcium. When available data from the four highest quality trials were pooled (n=1,317), there continued to be no evidence that vitamin D reduced the risk of falling (relative risk= 0.99, 95% confidence interval=0.89-1.11), although a single trial of vitamin D and calcium showed a positive effect.
Conclusion
Although there is insufficient evidence that vitamin D supplementation alone improves physical performance in older people, some data suggest a benefit from vitamin D combined with calcium supplementation, but this requires confirmation in large, well-designed trials.
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