Treatment of postmastectomy lymphedema with low-level laser therapy: a double blind, placebo-controlled trial
Carati CJ, Anderson SN, Gannon BJ, Piller NB
Cancer · 95 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2003-08-01 · Cancer · vol. 98 · número 6 · págs. 1114–1122
- Editorial
- Wiley
- Citado
- 172 citas · más que el 88% de estudios similares · 2.4× el promedio de su campo
- Referencias
- 32 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Lymphatic System and Diseases · Laser Applications in Dentistry and Medicine · Body Contouring and Surgery
- Palabras clave
- postmastectomy lymphedema, low-level laser therapy, limb volume reduction, extracellular fluid, tissue hardness, range of motion, breast cancer surgery complications
- MeSH
- axilla, extracellular space, humans, breast neoplasms, lymphedema, postoperative complications, tonometry, ocular, mastectomy, cross-over studies, double-blind method, adult, aged, aged, 80 and over, middle aged, female, low-level light therapy
4 autores
- Colin J. Carati🇦🇺 · autor de correspondenciaFlinders University
- Sandy Anderson🇦🇺Flinders University; Flinders Medical Centre
- Bren J. Gannon🇦🇺Flinders University
- Neil Piller🇦🇺Flinders University; Flinders Medical Centre
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The current study describes the results of a double blind, placebo-controlled, randomized, single crossover trial of the treatment of patients with postmastectomy lymphedema (PML) with low-level laser therapy (LLLT).
Methods
Participants received placebo or one cycle or two cycles of LLLT to the axillary region of their affected arm. They were monitored for reductions in affected limb volume, upper body extracellular tissue fluid distribution, dermal tonometry, and range of limb movement.
Results
There was no significant improvement reported immediately after any of the treatments. However, the mean affected limb volume was found to be significantly reduced at 1 month or 3 months of follow-up after 2 cycles of active laser treatment. Approximately 31% of subjects had a clinically significant reduction in the volume of their PML-affected arm (> 200 mLs) approximately 2-3 months after 2 cycles of treatment. There was no significant effect of placebo treatment, or one cycle of laser treatment, on affected limb volume. The extracellular fluid index of the affected and unaffected arms and torso were reported to be significantly reduced at 3 months after 2 cycles of laser therapy, and there was significant softening of the tissues in the affected upper arm. Treatment did not appear to improve range of movement of the affected arm.
Conclusions
Two cycles of laser treatment were found to be effective in reducing the volume of the affected arm, extracellular fluid, and tissue hardness in approximately 33% of patients with postmastectomy lymphedema at 3 months after treatment.
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