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Ensayo controlado aleatorizado2004Financiación no declarada

The effects of creatine supplementation on muscular performance and body composition responses to short-term resistance training overreaching

Volek JS, Ratamess NA, Rubin MR, Gómez AL, French DN, McGuigan MM, Scheett TP, Sharman MJ, Häkkinen K, Kraemer WJ

European journal of applied physiology · 57 citas

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Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2004-04-15 · Eur J Appl Physiol · vol. 91 · número 5-6 · págs. 628–637
Editorial
Springer Science+Business Media
Citado
107 citas · más que el 84% de estudios similares · 2.0× el promedio de su campo
Referencias
44 trabajos
Acceso
Acceso abierto (copia en repositorio) · CC-BY
Áreas de investigación
Muscle metabolism and nutrition · Sports Performance and Training · Exercise and Physiological Responses
Palabras clave
creatine monohydrate supplementation, muscle performance, body composition, lean body mass, testosterone, sex hormone-binding globulin, cortisol, insulin, growth hormone, insulin-like growth factor I, squatting, bench press, explosive power, high-volume training
MeSH
muscle, skeletal, humans, creatine, hormones, administration, oral, psychomotor performance, adaptation, physiological, body composition, blood pressure, heart rate, physical endurance, muscle contraction, physical education and training, dietary supplements, adult, male

10 autores

  • Jeff S. Volek🇺🇸 · autor de correspondenciaUniversity of Connecticut
  • Nicholas A. Ratamess🇺🇸University of Connecticut
  • Martyn R. Rubin🇺🇸University of Connecticut
  • A L. G mez🇺🇸University of Connecticut
  • Duncan N. French🇺🇸University of Connecticut
  • Michael M. McGuigan🇺🇸University of Connecticut
  • Timothy P. Scheett🇺🇸University of Connecticut
  • Matthew J. Sharman🇺🇸University of Connecticut
  • Keijo H�kkinen🇫🇮University of Jyväskylä
  • William J. Kraemer🇺🇸University of Connecticut

Resumen

El texto original del estudio, en el idioma en que se publicó.

To determine the effects of creatine supplementation during short-term resistance training overreaching on performance, body composition, and resting hormone concentrations, 17 men were randomly assigned to supplement with 0.3 g/kg per day of creatine monohydrate (CrM: n=9) or placebo (P: n=8) while performing resistance exercise (5 days/week for 4 weeks) followed by a 2-week taper phase. Maximal squat and bench press and explosive power in the bench press were reduced during the initial weeks of training in P but not CrM. Explosive power in the bench press, body mass, and lean body mass (LBM) in the legs were augmented to a greater extent in CrM ( P<or=0.05) by the end of the 6-week period. A tendency for greater 1-RM squat improvement ( P=0.09) was also observed in CrM. Total testosterone (TT) and the free androgen index (TT/SHBG) decreased in CrM and P, reaching a nadir at week 3, whereas sex hormone binding globulin (SHBG) responded in an opposite direction. Cortisol significantly increased after week 1 in CrM (+29%), and returned to baseline at week 2. Insulin was significantly depressed at week 1 (-24%) and drifted back toward baseline during weeks 2-4. Growth hormone and IGF-I levels were not affected. Therefore, some measures of muscular performance and body composition are enhanced to a greater extent following the rebound phase of short-term resistance training overreaching with creatine supplementation and these changes are not related to changes in circulating hormone concentrations obtained in the resting, postabsorptive state. In addition, creatine supplementation appears to be effective for maintaining muscular performance during the initial phase of high-volume resistance training overreaching that otherwise results in small performance decrements.

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