The effect of creatine supplementation on strength recovery after anterior cruciate ligament (ACL) reconstruction: a randomized, placebo-controlled, double-blind trial
Tyler TF, Nicholas SJ, Hershman EB, Glace BW, Mullaney MJ, McHugh MP
The American journal of sports medicine · 28 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2004-02-20 · Am J Sports Med · vol. 32 · número 2 · págs. 383–388
- Editorial
- SAGE Publishing
- Citado
- 38 citas · más que el 90% de estudios similares · 2.7× el promedio de su campo
- Referencias
- 30 trabajos
- Acceso
- De pago
- Áreas de investigación
- Knee injuries and reconstruction techniques · Muscle metabolism and nutrition · Sports Performance and Training
- Palabras clave
- creatine supplementation, anterior cruciate ligament reconstruction, strength recovery, muscle strength, muscle power, postoperative rehabilitation, quadriceps strength, hamstring strength, hip muscle strength, single-leg hop test
- MeSH
- anterior cruciate ligament, knee joint, humans, muscle weakness, knee injuries, atrophy, creatine, placebos, range of motion, articular, treatment outcome, administration, oral, double-blind method, dietary supplements, adult, female, male, anterior cruciate ligament injuries, plastic surgery procedures
6 autores
- Timothy F. Tyler🇺🇸Lenox Hill Hospital
- Stephen Nicholas🇺🇸Lenox Hill Hospital
- Elliott B. Hershman🇺🇸Lenox Hill Hospital
- Beth W. Glace🇺🇸Lenox Hill Hospital
- Michael J. Mullaney🇺🇸Lenox Hill Hospital
- Malachy P. McHugh🇺🇸Lenox Hill Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Creatine supplementation has been shown to augment training-induced strength gains. The purpose of this study was to examine the effect of creatine supplementation on recovery of muscle strength after anterior cruciate ligament (ACL) reconstruction.
Hypothesis
Creatine supplementation will facilitate strength gains after ACL reconstruction.
Study design
Double-blind, prospective, and randomized clinical trial.
Methods
Sixty patients were randomized into creatine or placebo groups. Quadriceps and hamstring strength and power were measured isokinetically. Hip flexor, abductor, and adductor strengths were measured with a handheld dynamometer prior to surgery and at 6 weeks, 12 weeks, or 6 months after surgery.
Results
From 6 weeks to 12 weeks after surgery, there were significant increases in strength on the involved side for knee extension (47%), knee flexion (27%), hip flexion (20%), hip abduction (9%), and hip adduction (17%). These strength improvements were unaffected by creatine supplementation with similar effects in the creatine and placebo groups. From 6 weeks to 12 weeks after surgery, there were significant increases in power on the involved side for knee extension (46%) and knee flexion (26%), but these effects were not affected by creatine supplementation. At 6 months, creatine supplementation did not affect outcome as measured by the single leg hop test for distance or the knee outcome score.
Conclusions
The results demonstrate that patients do not benefit from creatine supplementation during the first 12 weeks of rehabilitation after ACL reconstruction.
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