Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine
Haskell CF, Kennedy DO, Wesnes KA, Scholey AB
Psychopharmacology · 206 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2005-01-27 · Psychopharmacology (Berl) · vol. 179 · número 4 · págs. 813–825
- Editorial
- Springer Science+Business Media
- Citado
- 355 citas · más que el 98% de estudios similares · 8.0× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 29 trabajos
- Acceso
- De pago
- Áreas de investigación
- Coffee research and impacts · Sleep and Work-Related Fatigue · Neurotransmitter Receptor Influence on Behavior
- Palabras clave
- caffeine, caffeine withdrawal, reaction time, working memory, alertness, mental fatigue, jitteriness, caffeine dependence
- MeSH
- saliva, humans, caffeine, central nervous system stimulants, cross-over studies, double-blind method, affect, cognition, psychomotor performance, arousal, reaction time, dose-response relationship, drug, stimulation, chemical, reading, adolescent, adult, middle aged, female, male
4 autores
- Crystal F. Haskell‐Ramsay🇬🇧Northumbria University
- David O. Kennedy🇬🇧Northumbria University
- Keith Andrew Wesnes🇬🇧Northumbria University
- Andrew B Scholey🇬🇧 · autor de correspondenciaNorthumbria University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Rationale
The cognitive and mood effects of caffeine are well documented. However, the majority of studies in this area involve caffeine-deprived, habitual caffeine users. It is therefore unclear whether any beneficial findings are due to the positive effects of caffeine or to the alleviation of caffeine withdrawal.
Objectives
The present placebo-controlled, double-blind, balanced crossover study investigated the acute cognitive and mood effects of caffeine in habitual users and habitual non-users of caffeine.
Method
Following overnight caffeine withdrawal, 24 habitual caffeine consumers (mean=217 mg/day) and 24 habitual non-consumers (20 mg/day) received a 150 ml drink containing either 75 or 150 mg of caffeine or a matching placebo, at intervals of > or =48 h. Cognitive and mood assessments were undertaken at baseline and 30 min post-drink. These included the Cognitive Drug Research computerised test battery, two serial subtraction tasks, a sentence verification task and subjective visual analogue mood scales.
Results
There were no baseline differences between the groups' mood or performance. Following caffeine, there were significant improvements in simple reaction time, digit vigilance reaction time, numeric working memory reaction time and sentence verification accuracy, irrespective of group. Self-rated mental fatigue was reduced and ratings of alertness were significantly improved by caffeine independent of group. There were also group effects for rapid visual information processing false alarms and spatial memory accuracy with habitual consumers outperforming non-consumers. There was a single significant interaction of group and treatment effects on jittery ratings. Separate analyses of each groups' responses to caffeine revealed overlapping but differential responses to caffeine. Caffeine tended to benefit consumers' mood more while improving performance more in the non-consumers.
Conclusions
These results do not support a withdrawal alleviation model. Differences in the patterns of responses to caffeine by habitual consumers and habitual non-consumers may go some way to explaining why some individuals become caffeine consumers.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.