Effects of encapsulated green tea and Guarana extracts containing a mixture of epigallocatechin-3-gallate and caffeine on 24 h energy expenditure and fat oxidation in men
Bérubé-Parent S, Pelletier C, Doré J, Tremblay A
The British journal of nutrition · 119 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2005-09-01 · Br J Nutr · vol. 94 · número 3 · págs. 432–436
- Editorial
- Cambridge University Press
- Citado
- 202 citas · más que el 97% de estudios similares · 6.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 20 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Tea Polyphenols and Effects · Coffee research and impacts · Adipose Tissue and Metabolism
- Palabras clave
- green tea extract, epigallocatechin gallate, caffeine, thermogenesis, fat oxidation, lipid oxidation, blood pressure, catechins, dose-response relationship
- MeSH
- humans, paullinia, catechin, caffeine, central nervous system stimulants, plant extracts, calorimetry, indirect, analysis of variance, area under curve, cross-over studies, double-blind method, energy metabolism, oxidation-reduction, thermogenesis, dose-response relationship, drug, beverages, tea, adult, middle aged, male
4 autores
- Sonia Bérubé-Parent🇨🇦Université Laval
- Catherine Pelletier🇨🇦Université Laval
- Jean Doré🇨🇦Université Laval
- Angelo Tremblay🇨🇦 · autor de correspondenciaUniversité Laval
Resumen
El texto original del estudio, en el idioma en que se publicó.
It has been reported that green tea has a thermogenic effect, due to its caffeine content and probably also to the catechin, epigallocatechin-3-gallate (EGCG). The main aim of the present study was to compare the effect of a mixture of green tea and Guarana extracts containing a fixed dose of caffeine and variable doses of EGCG on 24 h energy expenditure and fat oxidation. Fourteen subjects took part to this randomized, placebo-controlled, double-blind, cross-over study. Each subject was tested five times in a metabolic chamber to measure 24 h energy expenditure, substrate oxidation and blood pressure. During each stay, the subjects ingested a capsule of placebo or capsules containing 200 mg caffeine and a variable dose of EGCG (90, 200, 300 or 400 mg) three times daily, 30 min before standardized meals. Twenty-four hour energy expenditure increased significantly by about 750 kJ with all EGCG-caffeine mixtures compared with placebo. No effect of the EGCG-caffeine mixture was observed for lipid oxidation. Systolic and diastolic blood pressure increased by about 7 and 5 mmHg, respectively, with the EGCG-caffeine mixtures compared with placebo. This increase was significant only for 24 h diastolic blood pressure. The main finding of the study was the increase in 24 h energy expenditure with the EGCG-caffeine mixtures. However, this increase was similar with all doses of EGCG in the mixtures.
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