Creatine monohydrate and resistance training increase bone mineral content and density in older men
Chilibeck PD, Chrusch MJ, Chad KE, Shawn Davison K, Burke DG
The journal of nutrition, health & aging · 42 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2006-01-12 · J Nutr Health Aging · vol. 9 · número 5 · págs. 352–3
- Editorial
- National Institutes of Health
- Citado
- 75 citas · más que el 85% de estudios similares · 2.0× el promedio de su campo
- Referencias
- 0 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Bone health and osteoporosis research · Nutrition and Health in Aging
- Palabras clave
- creatine monohydrate, resistance training, bone mineral content, bone mineral density, older men, sarcopenia, lean body mass, muscle mass
- MeSH
- muscle, skeletal, humans, creatine, absorptiometry, photon, analysis of variance, double-blind method, adaptation, physiological, aging, bone density, dose-response relationship, drug, weight-bearing, weight lifting, dietary supplements, aged, male
5 autores
- Philip David Chilibeck🇨🇦University of Saskatchewan
- Murray Justin Chrusch
- K E. Chad
- Kelly S. Davison
- D G Burke
Resumen
El texto original del estudio, en el idioma en que se publicó.
Our purpose was to determine the effects of creatine supplementation combined with resistance training on bone mineral content and density in older men. Twenty-nine older men (age 71 y) were randomized (double blind) to receive creatine (0.3 g/kg creatine for 5 d and 0.07 g/kg thereafter) or placebo while participating in resistance training (12 weeks). Bone mineral content and density were determined by dual energy X-ray absorptiometry before and after training. There was a time main effect for whole-body and leg bone mineral density (p < or = 0.05) with these measures increasing by approximately 0.5%, and 1%, respectively in the combined groups. There was a group by time interaction for arms bone mineral content, with the group receiving creatine increasing by 3.2% (p < 0.01) and the group receiving placebo decreasing by 1.0% (not significant). Changes in lean tissue mass of the arms correlated with changes in bone mineral content of the arms (r = 0.67; p < 0.01). Resistance training of 12 weeks increases bone mineral density in older men and creatine supplementation may provide an additional benefit for increasing regional bone mineral content. The increase in bone mineral content may be due to an enhanced muscle mass with creatine, with potentially greater tension on bone at sites of muscle attachment.
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