The effects of 6 months of increased water intake on blood sodium, glomerular filtration rate, blood pressure, and quality of life in elderly (aged 55-75) men
Spigt MG, Knottnerus JA, Westerterp KR, Olde Rikkert MG, Schayck CP
Journal of the American Geriatrics Society · 23 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- ZonMw
Según 1 financiador declarado.
Publicación
- Publicado
- 2006-01-24 · J Am Geriatr Soc · vol. 54 · número 3 · págs. 438–443
- Editorial
- Wiley
- Citado
- 29 citas · más que el 75% de estudios similares · 0.8× el promedio de su campo
- Referencias
- 29 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Electrolyte and hormonal disorders · Blood Pressure and Hypertension Studies · Sodium Intake and Health
- Palabras clave
- older men, blood sodium, glomerular filtration rate, blood pressure, quality of life, water turnover, deuterium dilution, older adults
- MeSH
- body water, humans, sodium, glomerular filtration rate, follow-up studies, aging, blood pressure, drinking, time factors, reference values, quality of life, aged, middle aged, male
5 autores
- Mark Spigt🇳🇱Maastricht University; Care and Public Health Research Institute
- J. André Knottnerus🇳🇱Maastricht University
- Klaas R. Westerterp🇳🇱Maastricht University
- Marcel G. M. Olde Rikkert🇳🇱Maastricht University
- Onno C. P. van Schayck🇳🇱Maastricht University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
To study whether there are any negative or positive effects of 6 months of increased fluid intake in reasonably healthy elderly men.
Design
Randomized trial.
Setting
Community-based.
Participants
One hundred forty-one healthy participants aged 55 to 75.
Intervention
One group was given the advice to increase their daily fluid intake by 1.5 L of water; the other group was given placebo medication (8 mL inactive syrup per day).
Measurements
At 6 months blood sodium, glomerular filtration rate (GFR), blood pressure, and quality of life (QOL) were measured. The changes in water turnover were measured using deuterium.
Results
Most subjects did not manage to increase their fluid intake by 1.5 L. The average increase in the intervention group was approximately 1 L. Twenty-four-hour water turnover in the water group was 359 mL (95% confidence interval=171-548) higher than that of the control group at 6-month follow-up. Blood pressure, sodium level, GFR, and QOL did not change significantly in either group during the intervention period. In addition, the cases reporting a worsening on the effect measures were equally distributed over the two study groups.
Conclusion
The advice to increase fluid intake by 1.5 L had no negative effects in reasonably healthy men aged 55 to 75.
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