Financiado en parte por Meat and Livestock Australia
Partial substitution of carbohydrate intake with protein intake from lean red meat lowers blood pressure in hypertensive persons
Hodgson JM, Burke V, Beilin LJ, Puddey IB
The American journal of clinical nutrition · 89 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
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Quién lo pagó
- Financiación
- Financiado por la industria
- Grupo de la industria
- Meat and Livestock Australia
Según 1 financiador declarado.
Publicación
- Publicado
- 2006-04-01 · Am J Clin Nutr · vol. 83 · número 4 · págs. 780–787
- Editorial
- Elsevier BV
- Citado
- 147 citas · más que el 97% de estudios similares · 6.3× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 57 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Blood Pressure and Hypertension Studies · Nutritional Studies and Diet · Sodium Intake and Health
- Palabras clave
- animal protein, dietary protein substitution, carbohydrate intake, hypertension, blood pressure, systolic blood pressure, fasting blood glucose, cardiovascular risk markers, dietary intervention
- MeSH
- humans, cardiovascular diseases, hypertension, body weight, potassium, sodium, dietary carbohydrates, blood glucose, lipids, dietary proteins, blood pressure, meat, middle aged, female, male
4 autores
- Jonathan M. Hodgson🇦🇺 · autor de correspondenciaThe University of Western Australia; Royal Perth Hospital; Harry Perkins Institute of Medical Research
- Valerie Burke🇦🇺The University of Western Australia; Royal Perth Hospital; Harry Perkins Institute of Medical Research
- Lawrence Joseph Beilin🇦🇺The University of Western Australia; Royal Perth Hospital; Harry Perkins Institute of Medical Research
- Ian B. Puddey🇦🇺The University of Western Australia; Royal Perth Hospital; Harry Perkins Institute of Medical Research
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Compared with carbohydrate intake, dietary intake of plant protein can lower blood pressure in humans, but the effects of animal protein intake on blood pressure have yet to be investigated.
Objective
We aimed to determine whether partial substitution of carbohydrate intake with animal protein intake from lean red meat changes blood pressure and other markers of cardiovascular disease risk in hypertensive persons.
Design
Hypertensive persons (n = 60) were recruited to an 8-wk parallel-design study. The participants were randomly assigned either to maintain their usual diet (control group) or to partially replace energy intake from carbohydrate-rich foods with protein from lean red meat (protein group). Measurements were performed at baseline and at the end of the intervention.
Results
Compared with the control group, the protein group had a significantly higher protein intake [x (95% CI) percent of energy: 5.3% (3.7%, 6.9%), P < 0.001] and a corresponding lower carbohydrate intake [-5.3% of energy (-7.9%, -2.7%), P < 0.001]. Body weight and intakes of fat, alcohol, and fiber were not significantly different between the groups. Compared with the control group, the clinic, 24-h, awake, and asleep systolic blood pressures were lower [-5.2 (-10.3, -0.1), -4.0 (-7.4, -0.6), -4.7 (-8.9, -0.5), and -4.7 (-10.3, -0.1) mm Hg, respectively, P < 0.05] and fasting plasma glucose concentrations were higher [0.33 mmol/L (0.09, 0.58 mmol/L), P = 0.008] in the protein group. These differences were independent of age, sex, and changes in weight, alcohol intake, or urinary sodium and potassium excretion. Diastolic blood pressure and heart rate, arterial compliance, blood lipids, and serum insulin were not significantly different between the groups.
Conclusion
Within the context of other studies, these results suggest that modest substitution of carbohydrate-rich foods with protein-rich foods may lower blood pressure in hypertensive persons.
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