Aerobic exercise and lipids and lipoproteins in patients with cardiovascular disease: a meta-analysis of randomized controlled trials
Kelley GA, Kelley KS, Franklin B
Journal of cardiopulmonary rehabilitation · 49 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Heart, Lung, and Blood Institute
- Gobierno
- NHLBI NIH HHS
- Subvenciones
- National Heart, Lung, and Blood Institute (R01 HL069802)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2006-05-01 · J Cardiopulm Rehabil · vol. 26 · número 3 · págs. 131–139
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 106 citas · más que el 99% de estudios similares · 13.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 37 trabajos
- Acceso
- Acceso abierto (copia en repositorio)
- Áreas de investigación
- Cardiovascular and exercise physiology · Lipoproteins and Cardiovascular Health · Physical Activity and Health
- Palabras clave
- aerobic exercise, cardiovascular disease, lipids, lipoproteins, HDL cholesterol, triglycerides, total cholesterol, LDL cholesterol, exercise therapy, dyslipidemia, sex differences, men, adults, randomized controlled trials, cardiovascular risk reduction, lifestyle intervention, physical activity interventions, exercise intensity, exercise duration, exercise frequency
- MeSH
- humans, cardiovascular diseases, lipids, lipoproteins, exercise, exercise therapy, retrospective studies, randomized controlled trials as topic, biomarkers, cardiac rehabilitation
3 autores
- George A. Kelley🇺🇸 · autor de correspondenciaWest Virginia University
- Kristi Sharpe Kelley🇺🇸 · autor de correspondenciaWest Virginia University; Beaumont Hospital, Royal Oak
- Barry Franklin🇺🇸West Virginia University; Beaumont Hospital, Royal Oak
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
Use the meta-analytic approach to examine the effects of aerobic exercise on lipids and lipoproteins in adults with cardiovascular disease (CVD).
Methods
Studies were retrieved via electronic databases, review of reference lists from retrieved articles, including reviews, and hand searching. Inclusion criteria were: (1) randomized controlled trials, (2) aerobic exercise >or=4 weeks as an intervention, (3) studies published in English language only between January 1, 1955 and January 1, 2005, (4) studies published in journals or as dissertations or master's theses, (5) human subjects >or=18 years, (6) all subjects diagnosed with some type of CVD, and (7) pre and post data available for total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and/or triglycerides (TG). Random-effects models were used for data analysis.
Results
Of the more than 3,000 studies reviewed, a total of 10 representing 1,260 subjects (580 exercise, 680 control) were included in our analysis. There was a statistically significant increase of 9% in HDL-C (mean +/- SEM, 3.7 +/- 1.3 mg/dL; 95% CI, 1.2 to 6.1 mg/dL) and a statistically significant decrease of 11% in TG (-19.3 +/- 5.4 mg/dL; 95% CI, -30.1 to -8.5 mg/dL), but no statistically significant decreases in TC or LDL-C (TC, -8.8 +/- 6.8 mg/dL; 95% CI, -22.3 to 4.7 mg/dL; LDL-C, -7.7 +/- 6.0 mg/dL; 95% CI, -19.5 to 4.2 mg/dL).
Conclusions
The present findings suggest that chronic aerobic exercise increases HDL-C and decreases TG in adults, especially men, with CVD.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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