Voluntary muscle function after creatine supplementation in acute hypobaric hypoxia
Baker-Fulco CJ, Fulco CS, Kellogg MD, Glickman E, Young AJ
Medicine and science in sports and exercise · 4 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2006-08-01 · Med Sci Sports Exerc · vol. 38 · número 8 · págs. 1418–1424
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 7 citas · más que el 61% de estudios similares · 0.4× el promedio de su campo
- Referencias
- 37 trabajos
- Acceso
- De pago
- Áreas de investigación
- High Altitude and Hypoxia · Muscle metabolism and nutrition · Biochemical effects in animals
- Palabras clave
- creatine supplementation, hypobaric hypoxia, muscular endurance, maximal voluntary contraction, knee extension, post-exercise recovery, high altitude
- MeSH
- leg, muscle, skeletal, humans, creatine, exercise test, analysis of variance, cross-over studies, double-blind method, muscle fatigue, muscle contraction, adult, male, hypoxia
5 autores
- Carol J. Baker-Fulco🇺🇸U.S. Army Research Institute of Environmental Medicine; United States Army
- Charles S. Fulco🇺🇸U.S. Army Research Institute of Environmental Medicine; United States Army
- Mark D. Kellogg🇺🇸Boston Children's Hospital; Harvard University
- Ellen L. Glickman🇺🇸Kent State University
- Andrew J. Young🇺🇸U.S. Army Research Institute of Environmental Medicine
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
To determine whether creatine (Cr) supplementation improves muscle performance during exposure to acute hypobaric hypoxia.
Methods
Seven healthy men (28 +/- 6 yr, mean +/- SD) performed submaximal intermittent static knee contractions interspersed with maximal voluntary contractions (MVCs) every minute to exhaustion (approximately 50% of rested MVC force) in normoxia and hypobaric hypoxia (separated by 3 d) after supplementation with Cr (20 g.d(-1) for 7 d then 5 g.d(-1) for 4-7 d) or placebo (Pla) in a double-blind, randomized crossover study. A 5-wk period without supplementation separated treatments. Each test day, subjects performed two bouts (separated by 2 min) at their preset submaximal force, 32 +/- 4% rested MVC).
Results
Rested MVC force (860 +/- 66 N) and MVC force at exhaustion (396 +/- 27 N; 47 +/- 3% rested MVC) did not differ among treatments or environments (P > 0.05). For bout 1, endurance time was shorter in hypobaria (26 +/- 3 min) than normoxia (34 +/- 2 min) (P 0.05). MVC force returned to similar levels (P >0.05) in bout 2 after recovery in all four sessions (to approximately 615 N). For bout 2, endurance time also was shorter in hypobaria (7 +/- 1 min) than normoxia (9 +/- 1 min) (P 0.05).
Conclusion
This study, which used an exercise model designed to impose the same target contraction force under all experimental conditions, found no effect of Cr on maximal force, muscle endurance, or recovery in normoxia or hypobaric hypoxia.
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