Fiber and magnesium intake and incidence of type 2 diabetes: a prospective study and meta-analysis
Schulze MB, Schulz M, Heidemann C, Schienkiewitz A, Hoffmann K, Boeing H
Archives of internal medicine · 342 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2007-05-14 · Arch Intern Med · vol. 167 · número 9 · pág. 956
- Editorial
- American Medical Association
- Citado
- 538 citas · más que el 100% de estudios similares · 22.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 55 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nutritional Studies and Diet · Food composition and properties · Magnesium in Health and Disease
- Palabras clave
- type 2 diabetes, dietary fiber, cereal fiber, dietary magnesium, fruit fiber, plant fibers, diabetes risk, dietary factors, European Prospective Investigation into Cancer and Nutrition
- MeSH
- humans, diabetes mellitus, type 2, magnesium, diet, incidence, risk factors, cohort studies, dietary fiber, adult, aged, middle aged, female, male, edible grain
1 autor
- Matthias Bernd Schulze🇩🇪 · autor de correspondenciaGerman Institute of Human Nutrition
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Prospective studies on fiber and magnesium intake and risk of type 2 diabetes mellitus were inconsistent. We examined associations between fiber and magnesium intake and risk of type 2 diabetes and summarized existing prospective studies by meta-analysis.
Methods
We conducted a prospective cohort study of 9702 men and 15 365 women aged 35 to 65 years who were observed for incident diabetes from 1994 to 2005. Dietary intake of fiber and magnesium were measured with a validated food-frequency questionnaire. We estimated the relative risk (RR) by means of Cox proportional hazards analysis. We searched PubMed through May 2006 for prospective cohort studies of fiber and magnesium intake and risk of type 2 diabetes. We identified 9 cohort studies of fiber and 8 studies of magnesium intake and calculated summary RRs by means of a random-effects model.
Results
During 176 117 person-years of follow-up, we observed 844 incident cases of type 2 diabetes in the European Prospective Investigation Into Cancer and Nutrition-Potsdam. Higher cereal fiber intake was inversely associated with diabetes risk (RR for extreme quintiles, 0.72 [95% confidence interval [CI], 0.56-0.93]), while fruit fiber (0.89 [95% CI, 0.70-1.13]) and vegetable fiber (0.93 [95% CI, 0.74-1.17]) were not significantly associated. Meta-analyses showed a reduced diabetes risk with higher cereal fiber intake (RR for extreme categories, 0.67 [95% CI, 0.62-0.72]), but no significant associations for fruit (0.96 [95% CI, 0.88-1.04]) and vegetable fiber (1.04 [95% CI, 0.94-1.15]). Magnesium intake was not related to diabetes risk in the European Prospective Investigation Into Cancer and Nutrition-Potsdam (RR for extreme quintiles, 0.99 [95% CI, 0.78-1.26]); however, meta-analysis showed a significant inverse association (RR for extreme categories, 0.77 [95% CI, 0.72-0.84]).
Conclusion
Higher cereal fiber and magnesium intakes may decrease diabetes risk.
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