Performance and metabolic responses to a high caffeine dose during prolonged exercise
Graham TE, Spriet LL
Journal of applied physiology (Bethesda, Md. : 1985) · 159 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 1991-12-01 · J Appl Physiol (1985) · vol. 71 · número 6 · págs. 2292–2298
- Editorial
- American Physiological Society
- Citado
- 338 citas · más que el 96% de estudios similares · 4.6× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 30 trabajos
- Acceso
- De pago
- Áreas de investigación
- Coffee research and impacts · Sports Performance and Training · Muscle metabolism and nutrition
- Palabras clave
- caffeine, endurance exercise, running performance, cycling performance, plasma epinephrine, norepinephrine, substrate metabolism, respiratory exchange ratio, free fatty acids, plasma glycerol, trained runners
- MeSH
- muscles, humans, epinephrine, glycerol, caffeine, glycogen, fatty acids, nonesterified, ventilation-perfusion ratio, exercise, physical endurance, adult, female, male
2 autores
- Terry E. Graham🇨🇦University of Guelph
- Lawrence L. Spriet🇨🇦University of Guelph
Resumen
El texto original del estudio, en el idioma en que se publicó.
The present study examined whether a high caffeine dose improved running and cycling performance and altered substrate metabolism in well-trained runners. Seven trained competitive runners [maximal O2 uptake (VO2max) 72.6 +/- 1.5 ml.kg-1.min-1] completed four randomized and double-blind exercise trials at approximately 85% VO2max; two trials running to exhaustion and two trials cycling to exhaustion. Subjects ingested either placebo (PL, 9 mg/kg dextrose) or caffeine (CAF, 9 mg/kg) 1 h before exercise. Endurance times were increased (P less than 0.05) after CAF ingestion during running (PL 49.2 +/- 7.2 min, CAF 71.0 +/- 11.0 min) and cycling (PL 39.2 +/- 6.5 min, CAF 59.3 +/- 9.9 min). Plasma epinephrine concentration [EPI] was increased (P less than 0.05) with CAF before running (0.22 +/- 0.02 vs. 0.44 +/- 0.08 nM) and cycling (0.31 +/- 0.06 vs. 0.45 +/- 0.06 nM). CAF ingestion also increased [EPI] (P less than 0.05) during exercise; PL and CAF values at 15 min were 1.23 +/- 0.13 and 2.51 +/- 0.33 nM for running and 1.24 +/- 0.24 and 2.53 +/- 0.32 nM for cycling. Similar results were obtained at exhaustion. Plasma norepinephrine was unaffected by CAF at rest and during exercise. CAF ingestion also had no effect on respiratory exchange ratio or plasma free fatty acid data at rest or during exercise. Plasma glycerol was elevated (P less than 0.05) by CAF before exercise and at 15 min and exhaustion during running but only at exhaustion during cycling. Urinary [CAF] increased to 8.7 +/- 1.2 and 10.0 +/- 0.8 micrograms/ml after the running and cycling trials.(ABSTRACT TRUNCATED AT 250 WORDS)
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