The effect of caffeine, green tea and tyrosine on thermogenesis and energy intake
Belza A, Toubro S, Astrup A
European journal of clinical nutrition · 68 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2007-09-19 · Eur J Clin Nutr · vol. 63 · número 1 · págs. 57–64
- Editorial
- Springer Nature
- Citado
- 116 citas · más que el 91% de estudios similares · 3.3× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 48 trabajos
- Acceso
- De pago
- Áreas de investigación
- Coffee research and impacts · Tea Polyphenols and Effects · Regulation of Appetite and Obesity
- Palabras clave
- caffeine, green tea extract, tyrosine, thermogenesis, resting metabolic rate, energy intake, appetite, hemodynamics, blood pressure, heart rate, respiratory quotient, appetite suppression
- MeSH
- humans, camellia sinensis, body weight, caffeine, tyrosine, central nervous system stimulants, plant extracts, basal metabolism, phytotherapy, cross-over studies, double-blind method, appetite, energy intake, thermogenesis, blood pressure, heart rate, respiration, tea, adult, male, overweight, young adult
3 autores
- Anita Belza🇩🇰 · autor de correspondenciaUniversity of Copenhagen
- S Toubro🇩🇰University of Copenhagen
- Arne Vernon Astrup🇩🇰University of Copenhagen
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
To investigate the effect of three different food ingredients tyrosine, green tea extract (GTE) and caffeine on resting metabolic rate and haemodynamics, and on ad libitum energy intake (EI) and appetite.
Methods
Twelve healthy, normal weight men (age: 23.7 +/- 2.6 years, mean +/- s.d.) participated in a four-way crossover, randomized, placebo-controlled, double-blind study. Treatments were administered as tablets of 500 mg GTE, 400 mg tyrosine, 50 mg caffeine, or placebo, and were separated by >3-day washout. The acute thermogenic response was measured in a ventilated hood system for 4 h following ingestion. Blood pressure, heart rate (HR), and subjective appetite sensations were assessed hourly and ad libitum EI 4 h post-dose.
Results
Caffeine induced a thermogenic response of 6% above baseline value (72 +/- 25 kJ per 4 h, mean +/- s.e.) compared to placebo (P<0.0001). The thermogenic responses to GTE and tyrosine were not significantly different from placebo. Tyrosine tended to increase 4-h respiratory quotient by 1% compared to placebo (0.01 +/- 0.005, P=0.05). Ad libitum EI was not significantly different between treatments but was reduced by 8% (-403 +/- 183 kJ), 8% (-400 +/- 335 kJ) and 3% (-151 +/- 377 kJ) compared to placebo after intake of tyrosine, GTE and caffeine, respectively. No significant difference in haemodynamics was observed between treatments.
Conclusions
Only caffeine was thermogenic in the given dose and caused no haemodynamic side effects. The sample size was probably too small to detect any appetite suppressant properties of the treatments. Further investigations are required.
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