Financiado en parte por Medela
The effects of fish oil supplementation in pregnancy on breast milk fatty acid composition over the course of lactation: a randomized controlled trial
Dunstan JA, Mitoulas LR, Dixon G, Doherty DA, Hartmann PE, Simmer K, Prescott SL
Pediatric research · 89 citas
Etiquetas de revisión
Financiado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiado por la industria
- Empresa
- Medela
Según 1 financiador declarado.
Publicación
- Publicado
- 2007-12-01 · Pediatr Res · vol. 62 · número 6 · págs. 689–694
- Editorial
- Springer Nature
- Citado
- 156 citas · más que el 97% de estudios similares · 6.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 16 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Fatty Acid Research and Health · Infant Nutrition and Health · Breastfeeding Practices and Influences
- Palabras clave
- fish oil supplementation, pregnancy, breast milk fatty acid composition, docosahexaenoic acid, eicosapentaenoic acid, n-3 long-chain polyunsaturated fatty acids, infant development, olive oil placebo, lactation
- MeSH
- head, erythrocyte membrane, milk, human, humans, body weight, docosahexaenoic acids, eicosapentaenoic acid, plant oils, cephalometry, body height, longitudinal studies, double-blind method, verbal behavior, psychomotor performance, breast feeding, gestational age, lactation, pregnancy, time factors, dietary supplements, adult, infant, female, infant nutritional physiological phenomena, prenatal nutritional physiological phenomena, olive oil
7 autores
- Janet A. Dunstan🇦🇺The University of Western Australia
- Leon R. Mitoulas🇦🇺The University of Western Australia
- Glenys Dixon🇦🇺The University of Western Australia
- Dorota A. Doherty🇦🇺The University of Western Australia
- Peter Edwin Hartmann🇦🇺The University of Western Australia
- Karen Norrie Simmer🇦🇺The University of Western Australia
- Susan L. Prescott🇦🇺 · autor de correspondenciaThe University of Western Australia
Resumen
El texto original del estudio, en el idioma en que se publicó.
This study evaluated the longitudinal effect of fish oil in pregnancy on breast milk fatty acid composition and infant outcomes. In a randomized, controlled trial, 98 women received 2.2 g docosahexaenoic acid (DHA) and 1.1 g eicosapentaenoic acid (EPA) or olive oil from 20 wk of gestation until delivery. Fatty acid composition in breast milk (at 3 d, 6 wk, and 6 mo) and infant erythrocyte membranes (at 1 y) were determined by gas liquid chromatography. Breast milk fatty acids were examined in relationship to growth and development. Compared with control group, breast milk from women who received fish oil had proportionally higher DHA and EPA levels at 3 d and 6 wk after delivery, but this difference was no longer apparent by 6 mo. Infant DHA status at 1 y of age was directly related to DHA levels at 3 d, 6 wk, and 6 mo postpartum (but not to antenatal supplementation). Both EPA and DHA in breast milk were positively correlated with Griffith's developmental scores including hand and eye coordination. Thus, supplementation in pregnancy was associated with increased n-3 long-chain polyunsaturated fatty acids (LCPUFAs) in breast milk, particularly in early lactation, and this was positively associated with infant DHA status at 1 y.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.