Effects of creatine supplementation on the onset of neuromuscular fatigue threshold and muscle strength in elderly men and women (64 - 86 years)
Stout JR, Sue Graves B, Cramer JT, Goldstein ER, Costa PB, Smith AE, Walter AA
The journal of nutrition, health & aging · 66 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2008-02-11 · J Nutr Health Aging · vol. 11 · número 6 · págs. 459–64
- Editorial
- National Institutes of Health
- Citado
- 101 citas · más que el 87% de estudios similares · 2.4× el promedio de su campo
- Referencias
- 38 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Nutrition and Health in Aging · Biochemical effects in animals
- Palabras clave
- creatine supplementation, neuromuscular fatigue, fatigue threshold, physical work capacity, grip strength, sit-to-stand, muscular endurance, older adults, aging, exercise capacity
- MeSH
- muscle, skeletal, humans, body weight, creatine, hand strength, activities of daily living, cross-over studies, double-blind method, task performance and analysis, muscle fatigue, dietary supplements, aged, aged, 80 and over, middle aged, female, male, muscle strength
7 autores
- Jeffrey R. Stout🇺🇸University of Oklahoma
- Barbara Sue Graves
- Joel T. Cramer
- Erica R. Goldstein
- Pablo Brando Costa
- Abbie E. Smith‐Ryan
- A A Walter
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
This study examined the effects of 14 days of creatine supplementation on the physical working capacity at fatigue threshold (PWCFT), maximal isometric grip strength (GRIP), sit-to-stand (STS), and body weight (BW) in elderly men and women.
Design
Using a double blind cross-over design, fifteen men (n = 7) and women (n = 8) (age +/- SD = 74.5 +/- 6.4 yrs) were randomly assigned to either the creatine (CR) (20g.d-1 during week 1 decreasing to 10g.d-1 at week 2) or Placebo (PL) group. After a 4 to 6 week washout period, the subjects were assigned the other treatment. Before (pre) and after (post) the supplementation period, participants performed a discontinuous, cycle ergometry test to determine the PWCFT. In addition, subjects performed STS, GRIP, BW test prior to and post treatment.
Setting
Southeastern part of the United States.
Results
Significant increases in GRIP (6.7%) and PWCFT (15.6%) from pre- to post-supplementation were found for the CR (p < 0.05) treatment, but no change for the PL treatment was observed. However, no significant change (p superior 0.05) was noted for STS or BW for either treatment.
Conclusion
These findings suggest that 14 days of CR supplementation may increase upper body grip strength and increase physical working capacity by delaying neuromuscular fatigue in the elderly men and women in this study. While more research is needed, CR supplementation may improve upper body grip strength and lower body muscle endurance which may be important for maintaining health and independent living in elderly men and women.
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