A creatine-protein-carbohydrate supplement enhances responses to resistance training
Cribb PJ, Williams AD, Hayes A
Medicine and science in sports and exercise · 35 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2007-11-01 · Med Sci Sports Exerc · vol. 39 · número 11 · págs. 1960–1968
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 75 citas · más que el 80% de estudios similares · 1.6× el promedio de su campo
- Referencias
- 34 trabajos
- Acceso
- Acceso abierto (copia en repositorio)
- Áreas de investigación
- Muscle metabolism and nutrition · Sports Performance and Training · Muscle Physiology and Disorders
- Palabras clave
- creatine monohydrate, resistance training, muscle hypertrophy, lean body mass, muscle strength, contractile proteins, muscle fiber cross-sectional area, muscle fiber type, creatine content, body composition, vastus lateralis, resistance-trained men
- MeSH
- humans, creatine, dietary carbohydrates, dietary proteins, double-blind method, body composition, weight lifting, dietary supplements, victoria, male
3 autores
- Paul J. Cribb🇦🇺Victoria University
- Andrew Dafydd Williams🇦🇺University of Tasmania
- Alan Hayes🇦🇺Victoria University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
Studies attributing gains in strength and lean body mass (LBM) to creatine monohydrate (CrM) during resistance exercise (RE) training have not assessed these changes alongside cellular and subcellular adaptations. Additionally, CrM-treated groups have seldom been compared with a group receiving a placebo similar in nitrogen and energy. The purpose of this study was to examine the effects of a CrM-containing protein-carbohydrate (PRO-CHO) supplement in comparison with a supplement containing a similar amount of nitrogen and energy on body composition, muscle strength, fiber-specific hypertrophy, and contractile protein accrual during RE training.
Methods
In a double-blind, randomized protocol, resistance-trained males were matched for strength and placed into one of three groups: protein (PRO), PRO-CHO, or the same PRO-CHO supplement (1.5 g x kg(-1) body weight x d(-1)) containing CrM (Cr-PRO-CHO) (0.1 g x kg(-1) body weight x d(-1)). Assessments were completed the week before and after a 10-wk structured, supervised RE program: strength (1RM, three exercises), body composition (DEXA), and vastus lateralis muscle biopsies for determination of muscle fiber type (I, IIa, IIx), cross-sectional area (CSA), contractile protein, and creatine content.
Results
Cr-PRO-CHO provided greater improvements in 1RM strength. At least 40% of the strength improvements could be attributed to hypertrophy of muscle involved in this exercise. Cr-PRO-CHO also resulted in greater increases in LBM, fiber CSA, and contractile protein compared with PRO and PRO-CHO.
Conclusions
In RE-trained participants, supplementation with Cr-PRO-CHO provided greater muscle hypertrophy than an equivalent dose of PRO-CHO, and this response was apparent at three levels of physiology (LBM, fiber CSA, and contractile protein content).
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