Enamel matrix derivative and low-level laser therapy in the treatment of intra-bony defects: a randomized placebo-controlled clinical trial
Ozcelik O, Cenk Haytac M, Seydaoglu G
Journal of clinical periodontology · 57 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2007-12-14 · J Clin Periodontol · vol. 35 · número 2 · págs. 147–156
- Editorial
- Wiley
- Citado
- 80 citas · más que el 92% de estudios similares · 4.0× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 105 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Periodontal Regeneration and Treatments · Laser Applications in Dentistry and Medicine · Oral microbiology and periodontitis research
- Palabras clave
- enamel matrix derivative, low-level laser therapy, periodontitis, periodontal regeneration, postoperative pain, wound healing, gingival recession, probing depth reduction, biomaterials
- MeSH
- humans, alveolar bone loss, mandibular diseases, maxillary diseases, dental enamel proteins, bone substitutes, treatment outcome, combined modality therapy, epidemiologic methods, wound healing, adult, middle aged, female, male, low-level light therapy, postoperative pain
3 autores
- Onur Özçelik🇹🇷 · autor de correspondenciaCukurova University
- M. Cenk Haytaç🇹🇷Cukurova University
- Gülşah Şeydaoğlu🇹🇷Cukurova University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Aim
The aim of this study was to evaluate the immediate post-operative pain, wound healing and clinical results after the application of an enamel matrix protein derivative (EMD) alone or combined with a low-level laser therapy (LLLT) for the treatment of deep intra-bony defects.
Material and methods
This study was an intra-individual longitudinal test of 12 months' duration conducted using a blinded, split-mouth, placebo-controlled and randomized design. In 22 periodontitis patients, one intra-bony defect was randomly treated with EMD+LLLT, while EMD alone was applied to the contra-lateral defect site. LLLT was used both intra- and post-operatively. Clinical measurements were performed by a blinded periodontist at the time of surgery, in the first week and in the first, second, sixth and 12th month. Visual analogue scale (VAS) scores were recorded for pain assessment.
Results
The results have shown that the treatment of intra-bony defects with EMD alone or EMD+LLLT leads to probing depth reduction and attachment-level gain. In addition, EMD+LLLT had resulted in less gingival recession (p<0.05), less swelling (p<0.001) and less VAS scores (p<0.02) compared with EMD alone.
Conclusion
This study shows that EMD is an effective, safe and predictable biomaterial for periodontal regeneration and LLLT may improve the effects of EMD by reducing post-operative complications.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.