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Ensayo controlado aleatorizado2008

Weight-loss diet that includes consumption of medium-chain triacylglycerol oil leads to a greater rate of weight and fat mass loss than does olive oil

St-Onge MP, Bosarge A

The American journal of clinical nutrition · 83 citas

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento
Consumo medido con
No se indica

Quién lo pagó

Financiación
Financiación independiente
Gobierno
National Center for Research Resources
Gobierno
NCRR NIH HHS
Subvenciones
National Center for Research Resources (M01RR00032); National Center for Research Resources (M01RR000032)

Según 2 financiadores declarados.

Publicación

Publicado
2008-03-01 · Am J Clin Nutr · vol. 87 · número 3 · págs. 621–626
Editorial
Elsevier BV
Citado
127 citas · más que el 91% de estudios similares · 3.4× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
26 trabajos
Acceso
Lectura gratuita
Áreas de investigación
Diet and metabolism studies · Fatty Acid Research and Health · Dietary Effects on Health
Palabras clave
medium-chain triglycerides, MCT oil, olive oil, weight loss, fat loss, trunk fat, energy expenditure, dietary fat quality, overweight adults, weight loss diet
MeSH
adipose tissue, humans, weight loss, triglycerides, plant oils, tomography, x-ray computed, absorptiometry, photon, waist-hip ratio, treatment outcome, diet, reducing, body composition, energy metabolism, adult, middle aged, female, male, overweight, olive oil

2 autores

  • Marie‐Pierre St‐Onge🇺🇸 · autor de correspondenciaSt. Luke's-Roosevelt Hospital Center; Columbia University
  • Aubrey Bosarge🇺🇸St. Luke's-Roosevelt Hospital Center; University of Alabama at Birmingham; Columbia University

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

Clinical studies have shown that consumption of medium-chain triacylglycerols (MCTs) leads to greater energy expenditure than does consumption of long-chain triacylglycerols. Such studies suggest that MCT consumption may be useful for weight management.

Objective

We aimed to determine whether consumption of MCT oil improves body weight and fat loss compared with olive oil when consumed as part of a weight-loss program.

Design

Forty-nine overweight men and women, aged 19-50 y, consumed either 18-24 g/d of MCT oil or olive oil as part of a weight-loss program for 16 wk. Subjects received weekly group weight-loss counseling. Body weight and waist circumference were measured weekly. Adipose tissue distribution was assessed at baseline and at the endpoint by use of dual-energy X-ray absorptiometry and computed tomography.

Results

Thirty-one subjects completed the study (body mass index: 29.8 +/- 0.4, in kg/m(2)). MCT oil consumption resulted in lower endpoint body weight than did olive oil (-1.67 +/- 0.67 kg, unadjusted P = 0.013). There was a trend toward greater loss of fat mass (P = 0.071) and trunk fat mass (P = 0.10) with MCT consumption than with olive oil. Endpoint trunk fat mass, total fat mass, and intraabdominal adipose tissue were all lower with MCT consumption than with olive oil consumption (all unadjusted P values < 0.05).

Conclusions

Consumption of MCT oil as part of a weight-loss plan improves weight loss compared with olive oil and can thus be successfully included in a weight-loss diet. Small changes in the quality of fat intake can therefore be useful to enhance weight loss.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

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