A diet rich in long chain omega-3 fatty acids modulates satiety in overweight and obese volunteers during weight loss
Parra D, Ramel A, Bandarra N, Kiely M, Martínez JA, Thorsdottir I
Appetite · 88 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- European Commission
Según 1 financiador declarado.
Publicación
- Publicado
- 2008-06-15 · Appetite · vol. 51 · número 3 · págs. 676–680
- Editorial
- Elsevier BV
- Citado
- 162 citas · más que el 97% de estudios similares · 7.8× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 33 trabajos
- Acceso
- De pago
- Áreas de investigación
- Fatty Acid Research and Health · Regulation of Appetite and Obesity · Aquaculture Nutrition and Growth
- Palabras clave
- n-3 long-chain polyunsaturated fatty acids, satiety, hunger, weight loss, obesity, overweight, calorie-restricted diet, erythrocyte membrane fatty acids, n-6/n-3 ratio, postprandial satiety, dietary fatty acid intake
- MeSH
- erythrocyte membrane, humans, obesity, weight loss, dietary fats, unsaturated, fatty acids, omega-3, body mass index, diet, reducing, patient compliance, hunger, satiation, postprandial period, adult, female, male, overweight, young adult
6 autores
- Dolores Parra🇪🇸Universidad de Navarra
- Alfons Ramel🇮🇸University of Iceland; National University Hospital of Iceland
- Narcisa Maria Bandarra🇵🇹Instituto de Investigacao das Pescas e do Mar
- Mairead E Kiely🇮🇪University College Cork
- José Alfredo Martínez🇪🇸 · autor de correspondenciaUniversidad de Navarra
- Inga Þórsdóttir🇮🇸University of Iceland; National University Hospital of Iceland
Resumen
El texto original del estudio, en el idioma en que se publicó.
Long chain omega-3 fatty acids (LC n-3 FA) are considered nutritional factors with a potential to modulate food intake. Thus, the aim of the current study was to determine whether appetite could be affected by LC n-3 FA when included in a calorie-restricted diet to treat overweight or obesity. Appetite was explored in volunteers (31+/-5 years; BMI: 28.3+/-1.5 kg/m(2)) during the last 2 weeks of an 8-week energy-restricted balanced diet (weight loss=-5.9+/-3.1%) providing either a low (1300 mg/day; n=121) of LC n-3 FA. Erythrocyte membrane fatty acids were measured to detect diet-related changes in fatty acids and a validated visual analogue scale (VAS) was used to measure hunger sensations directly after and 2h after a test dinner. The LC n-3 FA content in erythrocyte membrane was lower in the low LC n-3 FA group (10.5+/-2.5% vs. 12.5+/-2.6%; p<0.001) after the intervention. The VAS assessment revealed lower hunger sensations in the high LC n-3 FA group immediately after the test dinner (fullness: p=0.045) and after 120 min (fullness: p=0.008; hunger: p=0.039). Correlation analysis showed a positive relation between n-3 FA/n-6 FA ratio in erythrocyte membrane and fullness 2h postprandial (r=0.139; p=0.032). In conclusion, LC n-3 FA intake modulates postprandial satiety in overweight and obese volunteers during weight loss. Further research is needed to investigate whether LC n-3 FA improve compliance to the nutritional treatment of overweight and obesity as well as weight loss maintenance.
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