Creatine supplementation does not affect clinical health markers in football players
Cancela P, Ohanian C, Cuitiño E, Hackney AC
British journal of sports medicine · 13 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2008-09-01 · Br J Sports Med · vol. 42 · número 9 · págs. 731–735
- Editorial
- BMJ
- Citado
- 29 citas · más que el 65% de estudios similares · 0.5× el promedio de su campo
- Referencias
- 38 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Sports Performance and Training · Biochemical effects in animals
- Palabras clave
- creatine monohydrate, creatine supplementation, football players, creatine kinase, uric acid, serum glucose, liver function, renal function, weight gain, ATP resynthesis, glucoregulation, maltodextrin placebo
- MeSH
- humans, creatine, creatinine, uric acid, blood glucose, double-blind method, physical education and training, soccer, dietary supplements, adult, male
4 autores
- P Cancela🇺🇾Universidad de la República de Uruguay
- Carlos Ohanian🇺🇾 · autor de correspondenciaUniversidad de la República de Uruguay; Hospital de Clínicas
- Eduardo Cuitiño🇺🇾Universidad de la República de Uruguay
- A. C. Hackney🇺🇸University of North Carolina at Chapel Hill
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
To study the effects of 8-week creatine monohydrate (CrM) supplementation on blood and urinary clinical health markers in football players.
Methods
14 football players were randomly assigned in a double-blinded fashion to Cre (n = 7) or Pla (n = 7) group. The Cre group ingested 15 g/day of CrM for 7 days and 3 g/day for the remaining 49 days, whereas the Pla group ingested maltodextrin following the same protocol. Football-specific training was performed during the study. Total body mass was determined and blood and urine samples were analysed for metabolic, hepatic, renal and muscular function markers, before and after supplementation.
Results
A gain of total body mass was observed after CrM intake, but not with placebo. Blood and urinary markers remained within normal reference values. There were no significant changes in renal and hepatic markers after CrM intake. However, total creatine kinase (CK) activity significantly increased, and uric acid level tended to decrease after CrM use. Likewise, serum glucose decreased in the Cre group following supplementation. No significant differences in urine parameters were found in either group after supplementation.
Conclusions
8 weeks of CrM supplementation had no negative effects on blood and urinary clinical health markers in football players. Properties of CrM may, however, be associated with an increase in CK activity, improving the efficiency for ATP resynthesis, a phenomenon indirectly confirmed by the decreasing tendency in uric acid concentration. Furthermore, CrM seems to slightly influence glucoregulation in trained subjects.
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