The effect of caffeine on retrobulbar hemodynamics
Ozkan B, Yüksel N, Anik Y, Altintas O, Demirci A, Cağlar Y
Current eye research · 35 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2008-01-01 · Curr Eye Res · vol. 33 · número 9 · págs. 804–809
- Editorial
- Taylor & Francis
- Citado
- 45 citas · más que el 78% de estudios similares · 0.9× el promedio de su campo
- Referencias
- 33 trabajos
- Acceso
- De pago
- Áreas de investigación
- Glaucoma and retinal disorders · Coffee research and impacts · Retinal Imaging and Analysis
- Palabras clave
- caffeine, retrobulbar hemodynamics, intraocular pressure, resistance index, vascular resistance, ophthalmic artery, ciliary arteries, glaucoma, blood pressure
- MeSH
- orbit, ciliary arteries, ophthalmic artery, retinal artery, humans, caffeine, central nervous system stimulants, ultrasonography, doppler, color, blood flow velocity, administration, oral, prospective studies, double-blind method, blood pressure, heart rate, intraocular pressure, adult, female, male
6 autores
- Berna Özkan🇹🇷Kocaeli Üniversitesi
- Nurşen Yüksel🇹🇷Kocaeli Üniversitesi
- Yonca Akgoz ANIK🇹🇷Kocaeli Üniversitesi
- Özgül Altıntaş🇹🇷Kocaeli Üniversitesi
- Ali Demırcı🇹🇷Kocaeli Üniversitesi
- Yusuf Çağlar🇹🇷Kocaeli Üniversitesi
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
To investigate the acute effect of caffeine on intraocular pressure and retrobulbar blood flow velocity.
Methods
In this randomized, double-masked, placebo-controlled, prospective study, we examined the effects of single 300-mg oral administration of caffeine on retrobulbar arteries' hemodynamics by using color Doppler ultrasonography imaging in healthy human volunteers. The subjects were divided into two groups; group 1 received a 300-mg caffeine tablet and group 2 received placebo. Measurements were obtained in two eyes at baseline, and 1 hr after acute ingestion of caffeine. Blood pressure, pulse rate, and intraocular pressure were monitored.
Results
When compared with placebo, no significant change in mean blood pressure or intraocular pressure was observed after administration of caffeine. No significant differences were detected in the peak systolic and end diastolic velocities of retrobulbar arteries, compared with baseline values. Resistive index of ophthalmic, central retinal, and short posterior nasal ciliary artery were significantly increased after oral application of caffeine in group 1 (p<0.05).
Conclusion
The vascular resistance of the retrobulbar vessels appears to be altered by caffeine consumption. Further studies are needed to investigate the effects of caffeine on hemodynamics in patients with glaucoma.
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