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Substrate metabolism and exercise performance with caffeine and carbohydrate intake

Hulston CJ, Jeukendrup AE

Medicine and science in sports and exercise · 43 citas

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Financiación no declarada

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Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2008-11-14 · Med Sci Sports Exerc · vol. 40 · número 12 · págs. 2096–2104
Editorial
Lippincott Williams & Wilkins
Citado
84 citas · más que el 93% de estudios similares · 3.9× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
41 trabajos
Acceso
De pago
Áreas de investigación
Coffee research and impacts · Muscle metabolism and nutrition · Sports Performance and Training
Palabras clave
caffeine, carbohydrate intake, glucose oxidation, glucose kinetics, exercise performance, endurance cycling, time trial performance, substrate metabolism, endurance cyclists
MeSH
humans, caffeine, dietary carbohydrates, glucose, central nervous system stimulants, placebos, task performance and analysis, oxidation-reduction, bicycling, adult, male, gas chromatography-mass spectrometry

2 autores

  • Carl J. Hulston🇬🇧University of Birmingham
  • Asker Erik Jeukendrup🇬🇧University of Birmingham

Resumen

El texto original del estudio, en el idioma en que se publicó.

Purpose

1) To investigate the effect of caffeine on exogenous carbohydrate (CHO) oxidation and glucose kinetics during exercise; and 2) to determine whether combined ingestion of caffeine and CHO enhanced cycling performance compared with CHO alone.

Methods

Ten endurance-trained cyclists performed three experimental trials consisting of 105 min steady-state (SS) cycling at 62% VO2max followed by a time trial (TT) lasting approximately 45 min. During exercise, subjects ingested either of the following: a 6.4% glucose solution (GLU), a 6.4% glucose plus caffeine solution providing 5.3 mg kg(-1) of caffeine (GLU + CAF), or a placebo (PLA). Glucose solutions contained a trace amount of [U-C]glucose, and eight subjects received a primed continuous [6,6-H2]glucose infusion.

Results

Peak exogenous CHO oxidation rates were not significantly different between GLU and GLU + CAF trials (52.6 +/- 2.7 and 49.1 +/- 2.1 micromol kg.min(-1), respectively). Rates of appearance (Ra) and disappearance (Rd) of glucose were significantly higher with CHO ingestion than PLA (P < 0.01) but were not significantly different between GLU and GLU + CAF trials. Performance times were 43.45 +/- 0.86, 45.45 +/- 1.07, and 47.40 +/- 1.30 min for GLU + CAF, GLU, and PLA, respectively. Therefore, GLU + CAF ingestion enhanced TT performance by 4.6% (P < 0.05) compared with GLU and 9% (P < 0.05) compared with PLA.

Conclusion

The coingestion of caffeine (5.3 mg kg(-1)) with CHO during exercise enhanced TT performance by 4.6% compared with CHO and 9.0% compared with water placebo. However, caffeine did not influence exogenous CHO oxidation or glucose kinetics during SS exercise.

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