Green tea catechin plus caffeine supplementation to a high-protein diet has no additional effect on body weight maintenance after weight loss
Hursel R, Westerterp-Plantenga MS
The American journal of clinical nutrition · 58 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
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Publicación
- Publicado
- 2009-01-29 · Am J Clin Nutr · vol. 89 · número 3 · págs. 822–830
- Editorial
- Elsevier BV
- Citado
- 81 citas · más que el 95% de estudios similares · 4.8× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 70 trabajos
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- Áreas de investigación
- Tea Polyphenols and Effects · Coffee research and impacts · Regulation of Appetite and Obesity
- Palabras clave
- green tea, epigallocatechin gallate, caffeine, high-protein diet, obesity, very low calorie diet, thermogenesis, fat oxidation, fat-free mass, satiety, resting energy expenditure, respiratory quotient, fat mass
- MeSH
- humans, body weight, weight loss, glycerol, catechin, caffeine, insulin, leptin, blood glucose, fatty acids, nonesterified, triglycerides, dietary proteins, appetite, body composition, thermogenesis, tea, adolescent, adult, middle aged, female, male, young adult
2 autores
- Rick Hursel🇳🇱 · autor de correspondenciaMaastricht University
- Margriet S. Westerterp‐Plantenga🇳🇱Maastricht University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Green tea (epigallocatechin gallate + caffeine) and protein each were shown to improve body weight maintenance after weight loss.
Objective
We investigated the effect of a green tea-caffeine mixture added to a high-protein (HP) diet on weight maintenance (WM) after body weight loss in moderately obese subjects.
Design
A randomized, placebo-controlled, double-blind parallel trial was conducted in 80 overweight and moderately obese subjects [age (mean +/- SD): 44 +/- 2 y; body mass index (BMI; in kg/m(2)): 29.6 +/- 2.0] matched for sex, age, BMI, height, body mass, and with a habitually low caffeine intake. A very-low-energy diet intervention during 4 wk was followed by 3 mo of WM; during the WM period, the subjects received a green tea-caffeine mixture (270 mg epigallocatechin gallate + 150 mg caffeine/d) or placebo, both in addition to an adequate protein (AP) diet (50-60 g protein/d) or an HP diet (100-120 g protein/d).
Results
Subjects lost 7.0 +/- 1.6 kg, or 8.2 +/- 2.0%, body weight (P < 0.001). During the WM phase, WM, resting energy expenditure, and fat-free mass (FFM) increased relatively in both the HP groups and in the AP + green tea-caffeine mixture group (P < 0.05), whereas respiratory quotient and body fat mass decreased, all compared with the AP + placebo group. Satiety increased only in both HP groups (P < 0.05). The green tea-caffeine mixture was only effective with the AP diet.
Conclusion
The green tea-caffeine mixture, as well as the HP diet, improved WM independently through thermogenesis, fat oxidation, sparing FFM, and, for the HP diet, satiety; a possible synergistic effect failed to appear.
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