Conjugated linoleic acid combined with creatine monohydrate and whey protein supplementation during strength training
Cornish SM, Candow DG, Jantz NT, Chilibeck PD, Little JP, Forbes S, Abeysekara S, Zello GA
International journal of sport nutrition and exercise metabolism · 38 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Saskatchewan Health Research Foundation
- Gobierno
- Natural Sciences and Engineering Research Council of Canada
Según 2 financiadores declarados.
Publicación
- Publicado
- 2009-02-01 · Int J Sport Nutr Exerc Metab · vol. 19 · número 1 · págs. 79–96
- Editorial
- Human Kinetics
- Citado
- 57 citas · más que el 89% de estudios similares · 2.6× el promedio de su campo
- Referencias
- 128 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Sports Performance and Training · Exercise and Physiological Responses
- Palabras clave
- conjugated linoleic acid, creatine monohydrate, whey protein, resistance training, muscle strength, lean body mass, muscle thickness, bone resorption, oxidative stress, renal function, dietary supplementation, body composition, muscle hypertrophy, sarcopenia prevention, sarcopenic obesity
- MeSH
- muscle, skeletal, bone and bones, kidney, humans, creatine, linoleic acids, conjugated, dietary proteins, milk proteins, double-blind method, body composition, oxidative stress, drug synergism, dietary supplements, female, male, resistance training, young adult, whey proteins
8 autores
- Stephen M. Cornish🇨🇦University of Saskatchewan
- Darren Glenn Candow
- Nathan Jantz
- Philip David Chilibeck
- Jonathan P. Little
- Scott C. Forbes
- Saman Abeysekara
- Gordon Alexander Zello
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
The authors examined the combined effects of conjugated linoleic acid (CLA), creatine (C), and whey protein (P) supplementation during strength training.
Methods
Sixty-nine participants (52 men, 17 women; M +/- SD age 22.5 +/-2.5 yr) were randomly assigned (double-blind) to 1 of 3 groups: CCP (6 g/d CLA + 9 g/d C + 36 g/d P; n = 22), CP (C + P + placebo oil; n = 25), or P (P + placebo oil; n = 22) during 5 wk of strength training (4-5 sets, 6-12 repetitions, 6 d/wk). Measurements were taken for body composition (air-displacement plethysmography), muscle thickness (ultrasound) of the flexors and extensors of the elbow and knee, 1-repetition-maximum (1-RM) strength (leg press and bench press), urinary markers of bone resorption (N-telopeptides, NTx), myofibrillar protein catabolism (3-methylhistidine; 3-MH), oxidative stress (8-isoprostanes), and kidney function (microalbumin) before and after training.
Results
Contrast analyses indicated that the CCP group had a greater increase in bench-press (16.2% +/- 11.3% vs. 9.7% +/- 17.0%; p < .05) and leg-press (13.1% +/- 9.9% vs. 7.7% +/-14.2%; p < .05) strength and lean-tissue mass (2.4% +/- 2.8% vs. 1.3% +/-4.1%; p < .05) than the other groups combined. All groups increased muscle thickness over time (p < .05). The relative change in 3-MH (CCP -4.7% +/- 70.2%, CP -0.4% +/- 81.4%, P 20.3% +/- 75.2%) was less in the groups receiving creatine (p < .05), with the difference for NTx also close to significance (p = .055; CCP -3.4% +/- 66.6%, CP -3.9% +/- 64.9%, P 26.0% +/- 63.8%). There were no changes in oxidative stress or kidney function.
Conclusion
Combining C, CLA, and P was beneficial for increasing strength and lean-tissue mass during heavy resistance training.
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