The effects of dietary cholesterol-lowering on psychological symptoms: a randomised controlled study
Weidner G, Connor SL, Gerhard GT, Duell PB, Connor WE
Psychology, health & medicine · 8 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Oregon Health and Science University
- Universidad u hospital
- Oregon Clinical and Translational Research Institute
- Gobierno
- NIH Clinical Center
Según 3 financiadores declarados.
Publicación
- Publicado
- 2009-05-01 · Psychol Health Med · vol. 14 · número 3 · págs. 255–261
- Editorial
- Taylor & Francis
- Citado
- 12 citas · más que el 73% de estudios similares · 0.6× el promedio de su campo
- Referencias
- 24 trabajos
- Acceso
- De pago
- Áreas de investigación
- Lipoproteins and Cardiovascular Health · Nutritional Studies and Diet · Cholesterol and Lipid Metabolism
- Palabras clave
- dietary cholesterol, low-fat diet, high-fat diet, depression, hostility, psychological symptoms, serum cholesterol, LDL cholesterol, HDL cholesterol, complex carbohydrates, isocaloric diet, SCL-90-R
- MeSH
- humans, hypercholesterolemia, anticholesteremic agents, severity of illness index, aggression, depression, adolescent, adult, middle aged, female, male, young adult
5 autores
- Gerdi Weidner🇺🇸 · autor de correspondenciaSan Francisco State University
- Sonja L. Connor🇺🇸Oregon Health & Science University
- Glenn T. Gerhard🇺🇸Oregon Health & Science University
- Paul Barton Duell🇺🇸Oregon Health & Science University
- William E. Connor🇺🇸Oregon Health & Science University
Resumen
El texto original del estudio, en el idioma en que se publicó.
The relationship of plasma cholesterol-reducing interventions to emotional states, such as depression and hostility, remains a topic of debate. The present study employed a randomised, controlled design, and was conducted at a clinical research center to test the effect of dietary cholesterol-lowering on psychological symptoms. Ten women and eight men were randomly assigned to one of two counterbalanced diet cycles (low-fat versus high-fat diet; isocaloric; 6 weeks each; separated by a washout period). Analyses for repeated measures revealed that the low-fat diet significantly reduced total, LDL and HDL cholesterol, when compared with baseline and the high-fat diet. As expected, weight remained unchanged. Ratings of depression, hostility and global severity of psychological symptoms as measured by the SCL-90-R also improved significantly on the low-fat, high-complex carbohydrate diet when compared with baseline. These results suggest that plasma cholesterol-lowering in the context of a low-fat, high-complex carbohydrate diet may have a beneficial effect on psychological symptoms.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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