Financiado en parte por California Walnut Commission
Effects of walnut consumption on blood lipids and other cardiovascular risk factors: a meta-analysis and systematic review
Banel DK, Hu FB
The American journal of clinical nutrition · 184 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiado por la industria
- Grupo de la industria
- California Walnut Commission
- Gobierno
- National Institutes of Health
- Gobierno
- National Heart, Lung, and Blood Institute
- Gobierno
- NHLBI NIH HHS
- Subvenciones
- National Heart, Lung, and Blood Institute (HL60712); National Institutes of Health (HL 60712)
Según 4 financiadores declarados.
Publicación
- Publicado
- 2009-05-21 · Am J Clin Nutr · vol. 90 · número 1 · págs. 56–63
- Editorial
- Elsevier BV
- Citado
- 311 citas · más que el 88% de estudios similares · 2.3× el promedio de su campo
- Referencias
- 32 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Fatty Acid Research and Health
- Palabras clave
- walnut consumption, serum lipids, LDL cholesterol, total cholesterol, HDL cholesterol, triglycerides, cardiovascular risk factors, polyunsaturated fatty acids, antioxidant capacity, inflammatory markers, body weight, body mass index
- MeSH
- humans, juglans, cardiovascular diseases, cholesterol, lipids, diet, risk factors, reference values, female, male, cholesterol, ldl
2 autores
- Deirdre Banel🇺🇸 · autor de correspondenciaHarvard University
- Frank B. Hu🇺🇸Harvard University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Consumption of nuts has been associated with a decreased risk of cardiovascular disease events and death. Walnuts in particular have a unique profile: they are rich in polyunsaturated fatty acids, which may improve blood lipids and other cardiovascular disease risk factors.
Objectives
We aimed to conduct a literature review and a meta-analysis to combine the results from several trials and to estimate the effect of walnuts on blood lipids.
Design
Literature databases were searched for published trials that compared a specifically walnut-enhanced diet with a control diet. We conducted a random-effects meta-analysis of weighted mean differences (WMDs) of lipid outcomes.
Results
Thirteen studies representing 365 participants were included in the analysis. Diets lasted 4-24 wk with walnuts providing 10-24% of total calories. When compared with control diets, diets supplemented with walnuts resulted in a significantly greater decrease in total cholesterol and in LDL-cholesterol concentrations (total cholesterol: WMD = -10.3 mg/dL, P < 0.001; LDL cholesterol: WMD = -9.2 mg/dL, P < 0.001). HDL cholesterol and triglycerides were not significantly affected by walnut diets more than with control diets (HDL cholesterol: WMD = -0.2, P = 0.8; triglycerides: WMD = -3.9, P = 0.3). Other results reported in the trials indicated that walnuts provided significant benefits for certain antioxidant capacity and inflammatory markers and had no adverse effects on body weight [body mass index (kg/m(2)): WMD = -0.4, P = 0.5; weight (kg): WMD = -0.05, P = 0.97].
Conclusions
Overall, high-walnut-enriched diets significantly decreased total and LDL cholesterol for the duration of the short-term trials. Larger and longer-term trials are needed to address the effects of walnut consumption on cardiovascular risk and body weight.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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