Nut consumption and risk of type II diabetes in the Physicians' Health Study
Kochar J, Gaziano JM, Djoussé L
European journal of clinical nutrition · 42 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Heart, Lung, and Blood Institute
- Gobierno
- National Cancer Institute
- Gobierno
- NCI NIH HHS
- Gobierno
- NHLBI NIH HHS
- Subvenciones
- National Heart, Lung, and Blood Institute (HL-34595); National Heart, Lung, and Blood Institute (HL 26490); National Cancer Institute (CA 34944); National Cancer Institute (R01 CA034944); National Heart, Lung, and Blood Institute (R01 HL026490); National Cancer Institute (CA-097193); National Cancer Institute (R01CA097193); National Cancer Institute (CA 40360); National Heart, Lung, and Blood Institute (R01HL034595); National Cancer Institute (R01 CA040360)
Según 4 financiadores declarados.
Publicación
- Publicado
- 2009-09-16 · Eur J Clin Nutr · vol. 64 · número 1 · págs. 75–79
- Editorial
- Springer Nature
- Citado
- 65 citas · más que el 90% de estudios similares · 3.0× el promedio de su campo
- Referencias
- 24 trabajos
- Acceso
- Acceso abierto (copia en repositorio)
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Nutrition, Genetics, and Disease
- Palabras clave
- nut consumption, type 2 diabetes, diabetes risk, new-onset diabetes, dietary intake, male physicians, overweight and obesity, Physicians' Health Study
- MeSH
- humans, nuts, diabetes mellitus, type 2, diet, diet surveys, incidence, proportional hazards models, risk factors, models, biological, middle aged, male, surveys and questionnaires
3 autores
- Jinesh Kochar🇺🇸Medical College of Wisconsin
- J. Michael Gaziano🇺🇸Brigham and Women's Hospital; Harvard University; VA Boston Healthcare System
- Luc Djoussé🇺🇸 · autor de correspondenciaBrigham and Women's Hospital; Harvard University; VA Boston Healthcare System; Geriatric Research Education and Clinical Center
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background/objectives
While type II diabetes (DM) is a major cause of morbidity in the United States, limited data are available on the association between nut intake and incident DM. We sought to examine the association between nut consumption and the risk of DM.
Subjects/methods
Prospective cohort of 20 224 male participants of the Physicians' Health Study I. Nut consumption was estimated using a 19-item brief food frequency questionnaire, and incident DM was ascertained through yearly follow-up questionnaires. Cox regression was used to estimate relative risks of DM.
Results
The average age of the study participants was 54.4+/-9.4 years (range: 40.7-87.1). During a mean follow-up of 19.2 years, 1828 cases of DM occurred. The crude incidence rates of DM were 4.82, 4.85, 4.92, 4.16, 4.29 and 3.32 cases per 1000 person-years for individuals reporting nut consumption of rarely/never, <1, 1, 2-4, 5-6 and 7+ servings per week, respectively. While nut consumption was associated with a lower risk of DM in a model adjusted for age (P for tend 0.017), such relation was attenuated on additional control for other confounders (multivariable adjusted hazard ratios (95% confidence interval) for DM were 1.0 (reference), 1.06 (0.93-1.20), 1.10 (0.95-1.26), 0.97 (0.82-1.14), 0.99 (0.76-1.30) and 0.87 (0.61-1.24) from the lowest to the highest category of nut consumption, respectively (P for trend 0.99). No statistically significant association between nut consumption and DM was found in either lean or overweight/obese participants.
Conclusions
Our data do not show an association between nut consumption and incident DM in US male physicians.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.