The effects of creatine monohydrate supplementation with and without D-pinitol on resistance training adaptations
Kerksick CM, Wilborn CD, Campbell WI, Harvey TM, Marcello BM, Roberts MD, Parker AG, Byars AG, Greenwood LD, Almada AL, Kreider RB, Greenwood M
Journal of strength and conditioning research · 17 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Posiblemente financiado por la industria
- Universidad u hospital
- Baylor University
- Grupo de la industria
- National Strength and Conditioning Association
Según 2 financiadores declarados.
Publicación
- Publicado
- 2009-12-01 · J Strength Cond Res · vol. 23 · número 9 · págs. 2673–2682
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 39 citas · más que el 71% de estudios similares · 0.9× el promedio de su campo
- Referencias
- 30 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Sports Performance and Training · Biochemical effects in animals
- Palabras clave
- creatine monohydrate, D-pinitol, creatine supplementation, resistance training adaptation, body composition, lean body mass, strength, creatine uptake, creatine loading
- MeSH
- humans, inositol, creatine, anabolic agents, absorptiometry, photon, exercise test, drug therapy, combination, analysis of variance, double-blind method, safety, adaptation, physiological, body composition, weight lifting, dietary supplements, adolescent, adult, muscle strength, resistance training
12 autores
- Chad M. Kerksick🇺🇸University of Oklahoma Health Sciences Center; University of Oklahoma
- Colin Wilborn🇺🇸University of Mary Hardin–Baylor
- William I. Campbell🇺🇸University of South Florida
- Travis M. Harvey🇺🇸United States Military Academy
- B Marcello🇺🇸Stanford University
- Mike D. Roberts🇺🇸University of Oklahoma
- Adam G. Parker🇺🇸West Texas A&M University
- Allyn Byars🇺🇸Angelo State University
- Lori D. Greenwood🇺🇸 · autor de correspondenciaBaylor University
- Anthony L. Almada🇺🇸University of Oklahoma
- Richard B. Kreider🇺🇸University of Oklahoma; Texas A&M University
- Mike Greenwood🇺🇸 · autor de correspondenciaBaylor University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Coingestion of D-pinitol with creatine (CR) has been reported to enhance creatine uptake. The purpose of this study was to evaluate whether adding D-pinitol to CR affects training adaptations, body composition, whole-body creatine retention, and/or blood safety markers when compared to CR ingestion alone after 4 weeks of resistance training. Twenty-four resistance trained males were randomly assigned in a double-blind manner to creatine + pinitol (CRP) or creatine monohydrate (CR) prior to beginning a supervised 4-week resistance training program. Subjects ingested a typical loading phase (i.e., 20 g/d-1 for 5 days) before ingesting 5 g/d-1 the remaining 23 days. Performance measures were assessed at baseline (T0), week 1 (T1), and week 4 (T2) and included 1 repetition maximum (1RM) bench press (BP), 1RM leg press (LP), isokinetic knee extension, and a 30-second Wingate anaerobic capacity test. Fasting blood and body composition using dual-energy x-ray absorptiometry (DEXA) were determined at T1 and T3. Data were analyzed by repeated measures analysis of variance (ANOVA). Creatine retention increased (p 0.05). Significant improvements in upper- and lower-body strength and body composition occurred in both groups. However, significantly greater increases in lean mass and fat-free mass occurred in the CR group when compared to CRP (p <0.05). Adding D-pinitol to creatine monohydrate does not appear to facilitate further physiological adaptations while resistance training. Creatine monohydrate supplementation helps to improve strength and body composition while resistance training. Data from this study assist in determining the potential role the addition of D-pinitol to creatine may aid in facilitating training adaptations to exercise.
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