Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials
Chow RT, Johnson MI, Lopes-Martins RA, Lopes-Martins RA, Bjordal JM
Lancet (London, England) · 357 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2009-11-14 · Lancet · vol. 374 · número 9705 · págs. 1897–1908
- Editorial
- Elsevier BV
- Citado
- 613 citas · más que el 91% de estudios similares · 3.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 108 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Musculoskeletal pain and rehabilitation · Pain Management and Treatment
- Palabras clave
- low-level laser therapy, neck pain, acute neck pain, chronic neck pain, pain intensity, non-invasive pain management, placebo comparison, treatment side effects, long-term pain relief
- MeSH
- humans, neck pain, pain measurement, randomized controlled trials as topic, low-level light therapy
4 autores
- Roberta T Chow🇦🇺The University of Sydney
- Mark I. Johnson🇬🇧Leeds Beckett University
- Rodrigo AB Lopes-Martins🇧🇷Universidade de São Paulo
- Jan Magnus Bjordal🇳🇴Høgskolen i Bergen; University of Bergen
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Neck pain is a common and costly condition for which pharmacological management has limited evidence of efficacy and side-effects. Low-level laser therapy (LLLT) is a relatively uncommon, non-invasive treatment for neck pain, in which non-thermal laser irradiation is applied to sites of pain. We did a systematic review and meta-analysis of randomised controlled trials to assess the efficacy of LLLT in neck pain.
Methods
We searched computerised databases comparing efficacy of LLLT using any wavelength with placebo or with active control in acute or chronic neck pain. Effect size for the primary outcome, pain intensity, was defined as a pooled estimate of mean difference in change in mm on 100 mm visual analogue scale.
Findings
We identified 16 randomised controlled trials including a total of 820 patients. In acute neck pain, results of two trials showed a relative risk (RR) of 1.69 (95% CI 1.22-2.33) for pain improvement of LLLT versus placebo. Five trials of chronic neck pain reporting categorical data showed an RR for pain improvement of 4.05 (2.74-5.98) of LLLT. Patients in 11 trials reporting changes in visual analogue scale had pain intensity reduced by 19.86 mm (10.04-29.68). Seven trials provided follow-up data for 1-22 weeks after completion of treatment, with short-term pain relief persisting in the medium term with a reduction of 22.07 mm (17.42-26.72). Side-effects from LLLT were mild and not different from those of placebo.
Interpretation
We show that LLLT reduces pain immediately after treatment in acute neck pain and up to 22 weeks after completion of treatment in patients with chronic neck pain.
Funding
None.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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