Financiado en parte por California Walnut Commission
Long-term walnut supplementation without dietary advice induces favorable serum lipid changes in free-living individuals
Torabian S, Haddad E, Cordero-MacIntyre Z, Tanzman J, Fernandez ML, Sabate J
European journal of clinical nutrition · 50 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiado por la industria
- Grupo de la industria
- California Walnut Commission
Según 1 financiador declarado.
Publicación
- Publicado
- 2010-01-20 · Eur J Clin Nutr · vol. 64 · número 3 · págs. 274–279
- Editorial
- Springer Nature
- Citado
- 65 citas · más que el 96% de estudios similares · 6.1× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 25 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nuts composition and effects · Fatty Acid Research and Health · Nutritional Studies and Diet
- Palabras clave
- dietary fat, serum lipids, plasma total cholesterol, LDL cholesterol, triglycerides, HDL cholesterol, LDL/HDL ratio, hypercholesterolemia, habitual diet, long-term dietary intervention
- MeSH
- humans, juglans, cardiovascular diseases, cholesterol, triglycerides, diet, cross-over studies, dietary supplements, adult, aged, middle aged, female, male, cholesterol, ldl, cholesterol, hdl
6 autores
- Setareh Torabian‐Riasati🇺🇸 · autor de correspondenciaCalifornia State University, Northridge; Loma Linda University
- Ella Hasso Haddad🇺🇸Loma Linda University
- Zaida Cordero‐MacIntyre🇺🇸Loma Linda University
- Jay S. Tanzman🇺🇸Loma Linda University
- María Luz Fernández🇺🇸University of Connecticut
- Joan Sabaté🇺🇸Loma Linda University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background/objectives
Walnuts have been shown to reduce serum lipids in short-term well-controlled feeding trials. Little information exists on the effect and sustainability of walnut consumption for longer duration in a free-living situation.
Subjects/methods
A randomized crossover design in which 87 subjects with normal to moderate high plasma total cholesterol were initially assigned to a walnut-supplemented diet or habitual (control) diet for a 6-month period, then switched to the alternate dietary intervention for a second 6-month period. Each subject attended seven clinics 2 months apart. At each clinic, body weight was measured, and in five clinics (months 0, 4, 6, 10 and 12), a blood sample was collected.
Results
Our study showed that supplementing a habitual diet with walnuts (12% of total daily energy intake equivalent) improves the plasma lipid profile. This beneficial effect was more significant in subjects with high plasma total cholesterol at baseline. Significant changes in serum concentrations of total cholesterol (P=0.02) and triglycerides (P=0.03) were seen and nearly significant changes in low-density lipoprotein cholesterol (LDL-C) (P=0.06) were found. No significant change was detected in either high-density lipoprotein (HDL) cholesterol LDL to HDL ratio.
Conclusions
Including walnuts as part of a habitual diet favorably altered the plasma lipid profile. The lipid-lowering effects of walnuts were more evident among subjects with higher lipid baseline values, precisely those people with greater need of reducing plasma total and LDL-C.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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