Utilization of magnesium during hypokinesia and magnesium supplementation in healthy subjects
Zorbas YG, Kakuris KK, Federenko YF, Deogenov VA
Nutrition (Burbank, Los Angeles County, Calif.) · 6 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2010-04-05 · Nutrition · vol. 26 · número 11-12 · págs. 1134–1138
- Editorial
- Elsevier BV
- Citado
- 9 citas · más que el 16% de estudios similares · 0.0× el promedio de su campo
- Referencias
- 16 trabajos
- Acceso
- De pago
- Áreas de investigación
- Magnesium in Health and Disease · Magnesium Alloys: Properties and Applications · Nutrition and Health Studies
- Palabras clave
- magnesium supplementation, hypokinesia, plasma magnesium, hypomagnesemia, physical inactivity
- MeSH
- knee, plasma, urine, feces, humans, magnesium chloride, magnesium, biopsy, needle, walking, immobilization, motor activity, water-electrolyte balance, running, time factors, dietary supplements, adolescent, male, quadriceps muscle, young adult, sedentary behavior
4 autores
- Yan G. Zorbas🇧🇬Bulgarian Academy of Sciences
- Kostas K. Kakuris🇧🇬Bulgarian Academy of Sciences
- Yuri F. Federenko🇧🇬Bulgarian Academy of Sciences
- Viktor A. Deogenov · autor de correspondencia
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
The incompleteness of electrolyte utilization during hypokinesia and electrolyte supplementation is the defining factor of electrolyte metabolic changes, yet the effect of electrolyte supplementation and HK upon electrolyte utilization is poorly understood. To determine the influence of magnesium (Mg(2+)) supplementation and hypokinesia (diminished movement) on magnesium utilization, we investigated the use of Mg(2+) supplementation to establish its effect upon muscle Mg(2+) content and Mg2(2+) losses.
Methods
This study was conducted in 40 physically healthy male volunteers during a pre-experimental period of 30 d and an experimental period of 364 d. Subjects were equally divided into four groups: unsupplemented control subjects (UCSs), unsupplemented experimental subjects (UESs), supplemented control subjects (SCSs), and supplemented experimental subjects (SESs). A daily supplementation of 3.0 mmol of magnesium-chloride per kilogram of body weight was given to subjects in the SCS and SES groups.
Results
Muscle Mg(2+) content decreased (P < 0.05) and plasma Mg(2+) concentration and Mg(2+) loss in urine and feces increased (P < 0.05) in the SES and UES groups compared with their pre-experimental levels and values in their respective control groups (SCS and UCS). Muscle Mg(2+) content decreased more (P < 0.05) and plasma Mg(2+) concentration and Mg(2+) loss in urine and feces increased more (P < 0.05) in the SES group than in the UES group.The muscle Mg(2+) content and plasma Mg(2+) level and Mg(2+) losses did not change in the control groups.
Conclusion
Daily Mg(2+) supplementation during prolonged hypokinesia decreases more muscle Mg(2+) content and Mg(2+)-deficient muscle increases more Mg(2+) loss in healthy subjects indicating lower Mg(2+) utilization with than without Mg(2+) supplementation.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.