Caffeine and stress alter salivary alpha-amylase activity in young men
Klein LC, Bennett JM, Whetzel CA, Granger DA, Ritter FE
Human psychopharmacology · 37 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Center for Research Resources
- Gobierno
- NCRR NIH HHS
- Subvenciones
- National Center for Research Resources (M01 RR10732)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2010-06-29 · Hum Psychopharmacol · vol. 25 · número 5 · págs. 359–367
- Editorial
- Wiley
- Citado
- 54 citas · más que el 77% de estudios similares · 1.2× el promedio de su campo
- Referencias
- 37 trabajos
- Acceso
- De pago
- Áreas de investigación
- Coffee research and impacts · Stress Responses and Cortisol · Heart Rate Variability and Autonomic Control
- Palabras clave
- caffeine, psychological stress, salivary amylase, mental arithmetic stressor, sympathetic activation, heart rate, blood pressure, young men
- MeSH
- saliva, humans, caffeine, analysis of variance, double-blind method, stress, psychological, blood pressure, heart rate, dose-response relationship, drug, adolescent, adult, male, alpha-amylases, young adult
5 autores
- Laura Cousino Klein🇺🇸 · autor de correspondenciaPennsylvania State University
- Jeanette M. Bennett🇺🇸Pennsylvania State University
- Courtney A. Whetzel🇺🇸Pennsylvania State University
- Douglas Alan Granger🇺🇸Pennsylvania State University
- Frank E. Ritter🇺🇸Pennsylvania State University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
We examined the effects of caffeine and a psychological stressor on salivary alpha-amylase (sAA) in healthy young males (age 18-30 years) who consumed caffeine on a daily basis.
Methods
Using a between-subjects, double-blind, placebo-controlled design, 45 participants received either 200 or 400 mg of caffeine (Vivarin) or placebo, rested for 20 min, and then performed 20 min of mental arithmetic. Saliva samples (assayed for sAA and caffeine), blood pressure, and heart rate were taken before (baseline) and 15 min after the math stressor (stress).
Results
Baseline sAA activity did not differ among the treatment groups; however, there was a statistically significant time by caffeine group interaction. Changes in sAA activity across the session were dependent on the amount of caffeine consumed. Following the challenge period, sAA activity among the placebo group was the lowest and sAA activity among the 400 mg treatment group was the highest. Separate repeated-measures ANOVAs conducted for each drug treatment group revealed that sAA activity increased in response to stress and caffeine (i.e., 200 and 400 mg groups) but not to stress alone (i.e., placebo group).
Conclusions
Findings provide evidence for acute sAA changes in response to caffeine and stress in habitual caffeine users.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.