Laser photobiomodulation of proliferation of cells in culture: a review of human and animal studies
Peplow PV, Chung TY, Baxter GD
Photomedicine and laser surgery · 90 citas
Etiquetas de revisión
Financiación no declaradaSolo mecanismosDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Células o muestras de laboratorio
- Resultado principal
- Solo mecanismos
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2010-07-28 · Photomed Laser Surg · vol. 28 · número 1_suppl · págs. S3–40
- Editorial
- Mary Ann Liebert, Inc.
- Citado
- 144 citas · más que el 95% de estudios similares · 5.3× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 67 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Biofield Effects and Biophysics · Photodynamic Therapy Research Studies
- Palabras clave
- laser photobiomodulation, cell proliferation, laser irradiation, cell culture, cell viability, wavelength dependence, irradiance, laser therapy, wound healing, nerve repair, skeletal muscle injury
- MeSH
- cells, cultured, fibroblasts, endothelial cells, animals, humans, lasers, dose-response relationship, radiation, wound healing, cell proliferation, low-level light therapy
3 autores
- Philip V. Peplow🇳🇿 · autor de correspondenciaUniversity of Otago
- Tzu‐Yun Chung🇳🇿University of Otago
- David G. Baxter🇳🇿University of Otago
Resumen
El texto original del estudio, en el idioma en que se publicó.
Aim
The aim of this article was to review experimental studies of laser irradiation of human and animal cells in culture to assess the photobiomodulatory effects of such irradiation.
Background
Previous studies have shown that various types of cells respond differently to laser irradiation, depending on irradiation parameters. Cellular outcomes measured or examined include cell numbers, cell viability, and ultrastructural features. A review of these studies may provide a further insight into the clinical effects brought about by laser light on cells and tissues, including laser effects in wound healing and repair of nerves and skeletal muscle after injury.
Methods
A systematic review was completed of original research articles investigating the effects of laser therapy on human and animal cells in culture (January 2002 to September 2009). Relevant articles were primarily sourced from PubMed and Medline by using EndNote X1, and from secondary searches. Search terms were "cell proliferation," "laser therapy," "laser irradiation," "laser phototherapy," and "phototherapy."
Results
In total, 46 relevant articles were included in the review, comprising work completed on a variety of cell types. Although results consistently demonstrated the potential of laser irradiation to affect cellular proliferation in a wavelength- and dosage-dependent manner, the relevance of other key irradiation parameters, such as irradiance, to such effects remained unclear.
Conclusions
Findings from studies of cells in culture clearly demonstrate the ability of laser irradiation to modulate (typically stimulate) cellular proliferation. The relevance of some irradiation parameters remains occult and represents an important area for further research.
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