Combined photodynamic and low-level laser therapies as an adjunct to nonsurgical treatment of chronic periodontitis
Lui J, Corbet EF, Corbet EF, Jin L
Journal of periodontal research · 72 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- University of Hong Kong
Según 1 financiador declarado.
Publicación
- Publicado
- 2010-09-22 · J Periodontal Res · vol. 46 · número 1 · págs. 89–96
- Editorial
- Wiley
- Citado
- 124 citas · más que el 97% de estudios similares · 6.8× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 64 trabajos
- Acceso
- De pago
- Áreas de investigación
- Oral microbiology and periodontitis research · Laser Applications in Dentistry and Medicine · Periodontal Regeneration and Treatments
- Palabras clave
- chronic periodontitis, photodynamic therapy, low-level laser therapy, adjunctive periodontal therapy, non-surgical periodontal therapy, gingival crevicular fluid, IL-1β, bleeding on probing, probing depth, gingival recession
- MeSH
- gingival crevicular fluid, humans, treatment outcome, combined modality therapy, photochemotherapy, single-blind method, dental scaling, adult, middle aged, female, male, interleukin-1beta, chronic periodontitis, periodontal debridement, low-level light therapy
3 autores
- Jane Ching-Lam Lui🇭🇰University of Hong Kong
- EF Corbet🇭🇰University of Hong Kong
- LJ Jin🇭🇰 · autor de correspondenciaUniversity of Hong Kong
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background and objective
In recent years, there has been a growing interest in the use of dental lasers for treatment of periodontal diseases. The purpose of this short-term clinical trial was to evaluate the effects of a combination of photodynamic therapy with low-level laser therapy as an adjunct to nonsurgical treatment of chronic periodontitis.
Material and methods
Twenty-four nonsmoking adults with untreated chronic periodontitis were randomly assigned in a split-mouth design to receive scaling and root debridement with or without one course of adjunctive photodynamic therapy and low-level laser therapy within 5 d. Plaque, bleeding on probing, probing depth and gingival recession were recorded at baseline, 1 and 3 mo after the treatment. Gingival crevicular fluid was collected for assay of interleukin-1β levels at baseline, 1 wk and 1 mo.
Results
The test teeth achieved greater reductions in the percentage of sites with bleeding on probing and in mean probing depth at 1 mo compared with the control teeth (p < 0.05). A significant decrease in gingival crevicular fluid volume was observed in both groups at 1 wk (p < 0.001), with a further decrease at 1 mo in the test sites (p < 0.05). The test sites showed a greater reduction of interleukin-1β levels in gingival crevicular fluid at 1 wk than the control sites (p < 0.05). No significant differences in periodontal parameters were found between the test and control teeth at 3 mo.
Conclusions
The present study suggests that a combined course of photodynamic therapy with low-level laser therapy could be a beneficial adjunct to nonsurgical treatment of chronic periodontitis on a short-term basis. Further studies are required to assess the long-term effectiveness of the combination of photodynamic therapy with low-level laser therapy as an adjunct in nonsurgical treatment of periodontitis.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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