Red meat and a fortified manufactured toddler milk drink increase dietary zinc intakes without affecting zinc status of New Zealand toddlers
Morgan EJ, Heath AL, Szymlek-Gay EA, Gibson RS, Gray AR, Bailey KB, Ferguson EL
The Journal of nutrition · 19 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Diarios o recordatorios de alimentación
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- University of Otago
Según 1 financiador declarado.
Publicación
- Publicado
- 2010-10-28 · J Nutr · vol. 140 · número 12 · págs. 2221–2226
- Editorial
- Elsevier BV
- Citado
- 26 citas · más que el 82% de estudios similares · 1.3× el promedio de su campo
- Referencias
- 28 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Trace Elements in Health · Iron Metabolism and Disorders · Infant Nutrition and Health
- Palabras clave
- zinc intake, zinc status, red meat, zinc deficiency, toddlers, serum zinc, hair zinc, micronutrient fortification
- MeSH
- humans, zinc, placebos, diet, double-blind method, meat products, child, preschool, infant, new zealand
7 autores
- Emily J. Morgan🇳🇿University of Otago
- Anne‐Louise M. Heath🇳🇿University of Otago
- Ewa A. Szymlek‐Gay🇳🇿🇸🇪University of Otago; Umeå University
- Rosalind Susan Gibson🇳🇿University of Otago
- Andrew Robert Gray🇳🇿University of Otago
- Karl B. Bailey🇳🇿University of Otago
- Elaine Ferguson🇬🇧🇳🇿 · autor de correspondenciaLondon School of Hygiene & Tropical Medicine; University of Otago
Resumen
El texto original del estudio, en el idioma en que se publicó.
Evidence suggests that New Zealand (NZ) children are mildly zinc deficient and may respond to dietary change. A 20-wk randomized intervention trial was therefore conducted to determine whether an increased intake of red meat or consumption of a fortified manufactured toddler milk drink (FTMD, fortified with zinc and other micronutrients) would increase dietary zinc intakes and improve the biochemical zinc status of 12- to 20-mo-old NZ toddlers. Toddlers were randomized to a red meat intervention (n = 90), FTMD intervention (n = 45), or nonfortified milk placebo (n = 90). Study foods were provided. Adherence was assessed via monthly 7-d meat or milk recording diaries. Hair and serum zinc concentrations, and length and weight were measured at baseline and postintervention. Nutrient intakes were assessed via 3-d weighed food records at baseline, wk 4, and wk 18. At baseline, 38% of participants had low serum zinc concentrations despite seemingly adequate dietary zinc intakes (<4% below the Estimated Average Requirement). Dietary zinc intakes significantly increased by 0.8 mg/d (95% CI: 0.5, 1.1) in the meat group and 0.7 mg/d (95% CI: 0.2, 1.1) in the FTMD group compared with a decrease of -0.5 (95% CI: -0.8, -0.2) mg/d in the placebo group. No corresponding increases in serum or hair zinc concentrations were observed. Dietary zinc intakes achievable via interventions based on red meat or a FTMD are unlikely to improve biochemical zinc status in NZ toddlers. These results also question cutoffs used to define zinc deficiency in toddlers.
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