Metabolic effects of krill oil are essentially similar to those of fish oil but at lower dose of EPA and DHA, in healthy volunteers
Ulven SM, Kirkhus B, Lamglait A, Basu S, Elind E, Haider T, Berge K, Vik H, Pedersen JI
Lipids · 196 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2010-11-02 · Lipids · vol. 46 · número 1 · págs. 37–46
- Editorial
- Wiley
- Citado
- 303 citas · más que el 100% de estudios similares · 17.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 33 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Fatty Acid Research and Health · Edible Oils Quality and Analysis · Aquaculture Nutrition and Growth
- Palabras clave
- krill oil, fish oil, omega-3 polyunsaturated fatty acids, eicosapentaenoic acid, docosahexaenoic acid, docosapentaenoic acid, serum lipids, oxidative stress, inflammation, triglycerides, phospholipids, dietary supplementation, dose comparison
- MeSH
- animals, humans, euphausiacea, cholesterol, fatty acids, omega-3, docosahexaenoic acids, eicosapentaenoic acid, triglycerides, oils, fish oils, female, male
9 autores
- Stine Marie Ulven · autor de correspondencia
- Bente Kirkhus🇳🇴Nofima
- Amandine Lamglait🇳🇴Mills (Norway)
- Samar Basu🇸🇪Uppsala University
- Elisabeth Elind
- Trond Haider
- Kjetil Berge
- Hogne Vik
- Jan Ivar Pedersen🇳🇴University of Oslo
Resumen
El texto original del estudio, en el idioma en que se publicó.
The purpose of the present study is to investigate the effects of krill oil and fish oil on serum lipids and markers of oxidative stress and inflammation and to evaluate if different molecular forms, triacylglycerol and phospholipids, of omega-3 polyunsaturated fatty acids (PUFAs) influence the plasma level of EPA and DHA differently. One hundred thirteen subjects with normal or slightly elevated total blood cholesterol and/or triglyceride levels were randomized into three groups and given either six capsules of krill oil (N = 36; 3.0 g/day, EPA + DHA = 543 mg) or three capsules of fish oil (N = 40; 1.8 g/day, EPA + DHA = 864 mg) daily for 7 weeks. A third group did not receive any supplementation and served as controls (N = 37). A significant increase in plasma EPA, DHA, and DPA was observed in the subjects supplemented with n-3 PUFAs as compared with the controls, but there were no significant differences in the changes in any of the n-3 PUFAs between the fish oil and the krill oil groups. No statistically significant differences in changes in any of the serum lipids or the markers of oxidative stress and inflammation between the study groups were observed. Krill oil and fish oil thus represent comparable dietary sources of n-3 PUFAs, even if the EPA + DHA dose in the krill oil was 62.8% of that in the fish oil.
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